Genome-scale CRISPR-Cas9 screening in stem cells: theories, applications and challenges
Due to the rapid development of stem cell technology, there have been tremendous
advances in molecular biological and pathological research, cell therapy as well as …
advances in molecular biological and pathological research, cell therapy as well as …
[HTML][HTML] Allogeneic hematopoietic stem cell transplantation for chronic myelomonocytic leukemia: clinical and molecular genetic prognostic factors in a Nordic …
E Wedge, JW Hansen, I Dybedal, M Creignou… - … and cellular therapy, 2021 - Elsevier
Chronic myelomonocytic leukemia (CMML) is an aggressive disease in which survival after
allogeneic hematopoietic stem cell transplantation (HCT) remains relatively poor. An …
allogeneic hematopoietic stem cell transplantation (HCT) remains relatively poor. An …
Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders
Background The role of cytoreduction prior to hematopoietic cell transplant (HCT) for
patients with pediatric myelodysplastic syndrome (MDS) and related disorders remains …
patients with pediatric myelodysplastic syndrome (MDS) and related disorders remains …
The evolution of minimal residual disease: key insights based on a bibliometric visualization analysis from 2002 to 2022
Z Yu, L Xie, J Zhang, H Lin, T Niu - Frontiers in Oncology, 2023 - frontiersin.org
Background The topic of minimal residual disease (MRD) has emerged as a crucial subject
matter in the domain of oncology in recent years. The detection and monitoring of MRD have …
matter in the domain of oncology in recent years. The detection and monitoring of MRD have …
Measurable (Minimal) Residual Disease in Myelodysplastic Neoplasms (MDS): Current State and Perspectives
Simple Summary Myelodysplastic Neoplasms (MDS) are a type of blood cancer presenting
as ineffective production of blood cells, even though the bone marrow appears active …
as ineffective production of blood cells, even though the bone marrow appears active …
The identity card of T cells—clinical utility of T-cell receptor repertoire analysis in transplantation
There is a clear medical need to change the current strategy of “one-size-fits-all”
immunosuppression for controlling transplant rejection to precision medicine and targeted …
immunosuppression for controlling transplant rejection to precision medicine and targeted …
Differential effects of donor lymphocyte infusion upon treatment response and GVHD according to relapse level and donor sources in patients with myelodysplastic …
S Park, TY Kim, JH Lee, JY Lee… - Therapeutic …, 2021 - journals.sagepub.com
Introduction: Donor lymphocyte infusion (DLI) is one of the effective options for post-
transplant disease control of myelodysplastic syndrome (MDS). Its success or failure …
transplant disease control of myelodysplastic syndrome (MDS). Its success or failure …
Strategies for minimal residual disease detection: current perspectives
G Andreani, D Cilloni - Blood and Lymphatic Cancer: Targets and …, 2019 - Taylor & Francis
Currently, the post-remission treatment in acute leukemia is based on the genetic profile of
leukemic cells at diagnosis (ie, FLT3 ITD positivity) and on the level of measurable residual …
leukemic cells at diagnosis (ie, FLT3 ITD positivity) and on the level of measurable residual …
Getting personal with myelodysplastic syndromes: is now the right time?
Introduction: Commonly used scoring systems rely on blood counts, histological and
cytological examination of bone marrow and peripheral blood as well as cytogenetic …
cytological examination of bone marrow and peripheral blood as well as cytogenetic …
Next-generation sequencing for measurable residual Disease Assessment in Acute Leukemia
AE Kovach, G Raca… - Advances in …, 2021 - advancesinmolecularpathology.com
Minimal residual disease, or measurable residual disease (MRD), has emerged as one of
the most important independent prognostic factors in acute leukemia. Extrapolating from …
the most important independent prognostic factors in acute leukemia. Extrapolating from …