[HTML][HTML] Signaling pathways and targeted therapy for myocardial infarction
Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
Toll-like receptor 4 (TLR4) inhibitors: Current research and prospective
Y Zhang, X Liang, X Bao, W Xiao, G Chen - European journal of medicinal …, 2022 - Elsevier
Abstract Toll-like receptor 4 (TLR4), a member of the Toll-like receptor (TLR) family, is
involved in innate immunity and mediates inflammatory responses by recognizing …
involved in innate immunity and mediates inflammatory responses by recognizing …
[HTML][HTML] Calycosin as a novel PI3K activator reduces inflammation and fibrosis in heart failure through AKT–IKK/STAT3 axis
X Wang, W Li, Y Zhang, Q Sun, J Cao… - Frontiers in …, 2022 - frontiersin.org
Aim: Inflammation and fibrosis have been shown to be critical factors in heart failure (HF)
progression. Calycosin (Cal) is the major active component of Astragalus mongholicus …
progression. Calycosin (Cal) is the major active component of Astragalus mongholicus …
Activation of ULK1 to trigger FUNDC1-mediated mitophagy in heart failure: effect of Ginsenoside Rg3 intervention
X Wang, G Ling, Y Wei, W Li, Y Zhang, N Tan, W Li… - Phytomedicine, 2023 - Elsevier
Background Although the development of therapies for heart failure (HF) continues apace,
clinical outcomes are often far from ideal. Unc51-like-kinase 1 (ULK1)-mediated mitophagy …
clinical outcomes are often far from ideal. Unc51-like-kinase 1 (ULK1)-mediated mitophagy …
[HTML][HTML] Potential diagnostic biomarkers: 6 cuproptosis-and ferroptosis-related genes linking immune infiltration in acute myocardial infarction
M Miao, S Cao, Y Tian, D Liu, L Chen, Q Chai… - Genes & …, 2023 - nature.com
The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack
specificity and exist as false positives in other non-cardiac diseases. Previous studies …
specificity and exist as false positives in other non-cardiac diseases. Previous studies …
[HTML][HTML] Single Domain Antibody application in bacterial infection diagnosis and neutralization
Q Qin, H Liu, W He, Y Guo, J Zhang, J She… - Frontiers in …, 2022 - frontiersin.org
Increasing antibiotic resistance to bacterial infections causes a serious threat to human
health. Efficient detection and treatment strategies are the keys to preventing and reducing …
health. Efficient detection and treatment strategies are the keys to preventing and reducing …
Effect of TLR4/MyD88/NF‐kB axis in paraventricular nucleus on ventricular arrhythmias induced by sympathetic hyperexcitation in post‐myocardial infarction rats
K Wang, S You, H Hu, X Li, J Yin, Y Shi… - Journal of Cellular …, 2022 - Wiley Online Library
Sympathetic activation after myocardial infarction (MI) leads to ventricular arrhythmias (VAs),
which can result in sudden cardiac death (SCD). The toll‐like receptor 4 (TLR4)/myeloid …
which can result in sudden cardiac death (SCD). The toll‐like receptor 4 (TLR4)/myeloid …
Mesenchymal stem cell-derived extracellular vesicle-shuttled microRNA-302d-3p represses inflammation and cardiac remodeling following acute myocardial …
Y Liu, R Guan, J Yan, Y Zhu, S Sun, Y Qu - Journal of Cardiovascular …, 2022 - Springer
Our research intended to investigate the roles of mesenchymal stem cell (MSC)-derived
extracellular vesicles (EVs) in acute myocardial infarction (AMI) via delivery of microRNA …
extracellular vesicles (EVs) in acute myocardial infarction (AMI) via delivery of microRNA …
[HTML][HTML] Molecular mechanism of tanshinone against prostate cancer
W Li, T Huang, S Xu, B Che, Y Yu, W Zhang, K Tang - Molecules, 2022 - mdpi.com
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in
Europe and America. According to the data in the World Cancer Report 2020, the incidence …
Europe and America. According to the data in the World Cancer Report 2020, the incidence …
[HTML][HTML] The roles of the mitophagy inducer Danqi pill in heart failure: a new therapeutic target to preserve energy metabolism
X Wang, Y Jiang, Y Zhang, Q Sun, G Ling, J Jiang, W Li… - Phytomedicine, 2022 - Elsevier
Background Mitophagy can regulate mitochondrial homeostasis, preserve energy
metabolism and cardiomyocytes survival effectively to restrain the development of heart …
metabolism and cardiomyocytes survival effectively to restrain the development of heart …