Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …

Abstract Toll-like receptor 4 (TLR4), a member of the Toll-like receptor (TLR) family, is
involved in innate immunity and mediates inflammatory responses by recognizing …

Aim: Inflammation and fibrosis have been shown to be critical factors in heart failure (HF)
progression. Calycosin (Cal) is the major active component of Astragalus mongholicus …

Background Although the development of therapies for heart failure (HF) continues apace,
clinical outcomes are often far from ideal. Unc51-like-kinase 1 (ULK1)-mediated mitophagy …

The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack
specificity and exist as false positives in other non-cardiac diseases. Previous studies …

Increasing antibiotic resistance to bacterial infections causes a serious threat to human
health. Efficient detection and treatment strategies are the keys to preventing and reducing …

Sympathetic activation after myocardial infarction (MI) leads to ventricular arrhythmias (VAs),
which can result in sudden cardiac death (SCD). The toll‐like receptor 4 (TLR4)/myeloid …

Our research intended to investigate the roles of mesenchymal stem cell (MSC)-derived
extracellular vesicles (EVs) in acute myocardial infarction (AMI) via delivery of microRNA …

Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in
Europe and America. According to the data in the World Cancer Report 2020, the incidence …

Background Mitophagy can regulate mitochondrial homeostasis, preserve energy
metabolism and cardiomyocytes survival effectively to restrain the development of heart …