[HTML][HTML] Therapeutic advances and future prospects in progressive forms of multiple sclerosis
Identifying effective therapies for the treatment of progressive forms of multiple sclerosis
(MS) is a highly relevant priority and one of the greatest challenges for the global MS …
(MS) is a highly relevant priority and one of the greatest challenges for the global MS …
Antigen-specific tolerization and targeted delivery as therapeutic strategies for autoimmune diseases
AK Shakya, KS Nandakumar - Trends in biotechnology, 2018 - cell.com
The prevalence of autoimmune disorders is increasing steadily and there is no permanent
cure available. Immunomodulation through repeated exposure of antigens, known as …
cure available. Immunomodulation through repeated exposure of antigens, known as …
[HTML][HTML] Kappa free light chains and IgG combined in a novel algorithm for the detection of multiple sclerosis
M Gudowska-Sawczuk, J Tarasiuk, A Kułakowska… - Brain sciences, 2020 - mdpi.com
Background: It is well known that the cerebrospinal fluid (CSF) concentrations of free light
chains (FLC) and immunoglobulin G (IgG) are elevated in multiple sclerosis patients (MS) …
chains (FLC) and immunoglobulin G (IgG) are elevated in multiple sclerosis patients (MS) …
[HTML][HTML] Beyond the magic bullet: current progress of therapeutic vaccination in multiple sclerosis
B Willekens, N Cools - CNS drugs, 2018 - Springer
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system
(CNS) characterized by neuroinflammation, neurodegeneration and impaired repair …
(CNS) characterized by neuroinflammation, neurodegeneration and impaired repair …
[HTML][HTML] Recent advances in antigen-specific immunotherapies for the treatment of multiple sclerosis
O Kammona, C Kiparissides - Brain Sciences, 2020 - mdpi.com
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system and is
considered to be the leading non-traumatic cause of neurological disability in young adults …
considered to be the leading non-traumatic cause of neurological disability in young adults …
[HTML][HTML] A personalized approach in progressive multiple sclerosis: the current status of disease modifying therapies (DMTs) and future perspectives
E D'Amico, F Patti, A Zanghì, M Zappia - International journal of molecular …, 2016 - mdpi.com
Using the term of progressive multiple sclerosis (PMS), we considered a combined
population of persons with secondary progressive MS (SPMS) and primary progressive MS …
population of persons with secondary progressive MS (SPMS) and primary progressive MS …
Immunotherapy for Alzheimer's disease: rational basis in ongoing clinical trials
M Menéndez-González, P Pérez-Piñera… - Current …, 2011 - ingentaconnect.com
Amyloid-β (Aβ) immunotherapy has recently begun to gain considerable attention as a
potentially promising therapeutic approach to reducing the levels of Aβ in the Central …
potentially promising therapeutic approach to reducing the levels of Aβ in the Central …
Recent advances in the development of vaccines for chronic inflammatory autoimmune diseases
N Zhang, KS Nandakumar - Vaccine, 2018 - Elsevier
Chronic inflammatory autoimmune diseases leading to target tissue destruction and
disability are not only causing increase in patients' suffering but also contribute to huge …
disability are not only causing increase in patients' suffering but also contribute to huge …
[HTML][HTML] Molecular interventions towards multiple sclerosis treatment
Multiple sclerosis (MS) is an autoimmune life-threatening disease, afflicting millions of
people worldwide. Although the disease is non-curable, considerable therapeutic advances …
people worldwide. Although the disease is non-curable, considerable therapeutic advances …
DNA-based vaccines for multiple sclerosis: current status and future directions
N Fissolo, X Montalban, M Comabella - Clinical immunology, 2012 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that
mainly affects young adults between 20 and 40years of age and leads to significant …
mainly affects young adults between 20 and 40years of age and leads to significant …