Background Polypoidal choroidal vasculopathy (PCV), a subtype of age-related macular
degeneration (AMD), is a global leading cause of vision loss in older populations. Distinct …

All capillary endothelia, including those of the glomeruli, have a luminal cell surface layer
(ESL) consisting of glycoproteins, glycolipids, proteoglycans (PGs) and glycosaminoglycans …

The endothelial glycocalyx (GCX) plays a key role in the development of organ failure
following sepsis. Researchers have investigated GCX degradation caused by pathological …

Аннотация Современный взгляд на эндотелиальную дисфункцию в патогенезе многих
заболеваний включает, наряду с нарушением морфологии и функции клеток …

Background: Mitochondrial, lysosomal, and peroxisomal dysfunction; defective autophagy;
mitophagy; and pexophagy, as well as the loss of glycocalyx integrity are known contributors …

Purpose Hyaluronic acid plays an essential role in water retention of the intervertebral disc
(IVD) and thus provides flexibility and shock absorbance in the spine. Hyaluronic acid gets …

Abstract Background and Purpose: Diabetic vascular complication is a leading cause of
disability and mortality in diabetes patients. Low molecular weight fucoidan (LMWF) is a …

The endothelial glycocalyx (eGlx) constitutes the first barrier to protein in all blood vessels.
This is particularly noteworthy in the renal glomerulus, an ultrafiltration barrier. Leakage of …

The glycocalyx is a layer composed of carbohydrate side chains bound to core proteins that
lines the vascular endothelium. The integrity of the glycocalyx is essential for endothelial …

Endothelial permeability deterioration is involved in ventilator-induced lung injury (VILI). The
integrality of vascular endothelial glycocalyx (EG) is closely associated with endothelial …