The translational neuroscience of sleep: a contextual framework

MA Grandner, FX Fernandez - Science, 2021 - science.org
Sleep is entwined across many physiologic processes in the brain and periphery, thereby
exerting tremendous influence on our well-being. Yet sleep exists in a social-environmental …

Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

[HTML][HTML] Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm

RJ Reiter, R Sharma, MS Cucielo, DX Tan… - Cellular and Molecular …, 2023 - Springer
The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

[HTML][HTML] Metabolic contribution and cerebral blood flow regulation by astrocytes in the neurovascular unit

S Takahashi - Cells, 2022 - mdpi.com
The neurovascular unit (NVU) is a conceptual framework that has been proposed to better
explain the relationships between the neural cells and blood vessels in the human brain …

The glymphatic system's role in traumatic brain injury-related neurodegeneration

ME Peters, CG Lyketsos - Molecular psychiatry, 2023 - nature.com
In at least some individuals who suffer a traumatic brain injury (TBI), there exists a risk of
future neurodegenerative illness. This review focuses on the association between the brain …

[HTML][HTML] Meningeal lymphatics: an immune gateway for the central nervous system

GA Tavares, A Louveau - Cells, 2021 - mdpi.com
The recent (re) discovery of the meningeal lymphatic system has opened new theories as to
how immune cells traffic and interact with the central nervous system (CNS). While evidence …

[HTML][HTML] Glymphatic system and mitochondrial dysfunction as two crucial players in pathophysiology of neurodegenerative disorders

K Kopeć, S Szleszkowski, D Koziorowski… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases are a complex problem affecting millions of people around the
world. The pathogenesis is not fully understood, but it is known that both insufficiency of the …

Molecular, pathological, clinical, and therapeutic aspects of perihematomal edema in different stages of intracerebral hemorrhage

C Jiang, H Guo, Z Zhang, Y Wang, S Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Acute intracerebral hemorrhage (ICH) is a devastating type of stroke worldwide. Neuronal
destruction involved in the brain damage process caused by ICH includes a primary injury …

[HTML][HTML] Identification of ultra-rare genetic variants in pediatric acute onset neuropsychiatric syndrome (PANS) by exome and whole genome sequencing

R Trifiletti, HM Lachman, O Manusama, D Zheng… - Scientific reports, 2022 - nature.com
Abrupt onset of severe neuropsychiatric symptoms including obsessive–compulsive
disorder, tics, anxiety, mood swings, irritability, and restricted eating is described in children …

[HTML][HTML] Influence of interaction of cerebral fluids on ventricular deformation: A mathematical approach

G Valova, O Bogomyakova, A Tulupov, A Cherevko - Plos one, 2022 - journals.plos.org
This paper describes the effects of the interaction of cerebral fluids (arterial, capillary and
venous blood, cerebrospinal fluid) on ventricular wall displacement and periventricular …