Type 2 immunity mediates protective responses to helminths and pathological responses to
allergens, but it also has broad roles in the maintenance of tissue integrity, including wound …

IgE-mediated type I hypersensitivity reactions have many reported beneficial functions in
immune defense against parasites, venoms, toxins, etc. However, they are best known for …

Aberrant activation of CD4 TH 2 cells and excessive production of TH 2 cytokines such as IL-
4 and IL-13 have been implicated in the pathogenesis of allergic diseases. Generally, IL-4 …

Innate lymphoid cells and innate-like T cells in cancer — at the crossroads of innate and
adaptive immunity | Nature Reviews Cancer Skip to main content Thank you for visiting …

Introduction IQGAP3 possesses oncogenic actions; its impact on prostate cancer (PC)
remains unclear. Objective We will investigate IQGAP3′ s association with PC progression …

Polarized T helper cell (Th cell) responses are important determinants of host protection. Th
cell subsets tailor their functional repertoire of cytokines to their cognate antigens to …

Respiratory and digestive mucosal surfaces are continually exposed to common
environmental antigens, which include potential allergens. Although innocuous in healthy …

Helminths are parasitic worms that coevolve with their host, usually resulting in long-term
persistence through modulating host immunity. The multifarious mechanisms altering the …

Simple Summary Breast cancer is the leading cause of cancer deaths in women. The current
management of patients with breast cancer needs improvement in two aspects: risk …

Asthma and nasal polyposis often coexist and are frequently intertwined by tight pathogenic
links, mainly consisting of the cellular and molecular pathways underpinning type 2 airway …