Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor
(NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival …

Abstract Changes in the levels and activities of neurotrophic factors, such as brain-derived
neurotrophic factor (BDNF), have been described in a number of neurodegenerative …

Brain-derived neurotrophic factor has emerged as one of the most important molecules
involved in memory. Its wide role in different types of memories that depend on different …

Orexins (also known as hypocretins) are neuropeptides located exclusively in hypothalamic
neurons that have extensive projections throughout the central nervous system and bind two …

Brain-derived neurotrophic factor (BDNF) activates the receptor tropomyosin-related kinase
B (TrkB) with high potency and specificity, promoting neuronal survival, differentiation, and …

The Trk family of receptors play a wide variety of roles in physiological and disease
processes in both neuronal and non-neuronal tissues. Amongst these the TrkB receptor in …

It is well accepted that events that interfere with the normal program of neuronal
differentiation and brain maturation may be relevant for the etiology of psychiatric disorders …

In addition to the classic motor symptoms, Parkinson's disease (PD) is associated with a
variety of nonmotor symptoms that significantly reduce quality of life, even in the early stages …

In spite of the massive research for the identification of neurorestorative or neuroprotective
intervention for curing Parkinson's disease (PD), there is still lack of clinically proven …

Background Animal models of exercise and Parkinson's disease (PD) have found that the
physiologic use of exercise may interact with the neurodegenerative disease process, likely …