Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

The persistent increase in the worldwide burden of type 2 diabetes mellitus (T2D) and the
accompanying rise of its complications, including cardiovascular disease, necessitates our …

Our understanding of how the gut microbiome interacts with its human host has been
restrained by limited access to longitudinal datasets to examine stability and dynamics, and …

Context Intermittent fasting (IF) is an effective strategy to improve cardiometabolic health.
Objective The objective of this work is to examine the effects of IF on cardiometabolic risk …

Elevated branched-chain amino acids (BCAAs) are associated with obesity and insulin
resistance. How long-term dietary BCAAs impact late-life health and lifespan is unknown …

Background: Blood chemicals are routinely measured in clinical or preclinical research
studies to diagnose diseases, assess risks in epidemiological research, or use metabolomic …

Background: Whereas regular exercise is associated with lower risk of cardiovascular
disease and mortality, mechanisms of exercise-mediated health benefits remain less clear …

The interaction between gut microbiota and host plays a central role in health. Dysbiosis,
detrimental changes in gut microbiota, and inflammation have been reported in non …

Integrating genetic information with metabolomics has provided new insights into genes
affecting human metabolism. However, gene-metabolite integration has been primarily …

Importance Prior studies have raised concern about maternal acetaminophen use during
pregnancy and increased risk of attention-deficit/hyperactivity disorder (ADHD) and autism …