Importance In patients who require mechanical ventilation for acute hypoxemic respiratory
failure, further reduction in tidal volumes, compared with conventional low tidal volume …

Acute respiratory distress syndrome (ARDS) is a life-threatening condition, characterized by
diffuse inflammatory lung injury. Since the coronavirus disease 2019 (COVID-19) pandemic …

Nitric oxide (NO) is a key molecule in the biology of human life. NO is involved in the
physiology of organ viability and in the pathophysiology of organ dysfunction, respectively …

Background The impact of underlying comorbidities on the clinical presentation,
management and outcomes in patients with ARDS is poorly understood and deserves …

Purpose We determined the incidence of hypercapnia and associations with outcome in
invasively ventilated COVID–19 patients. Methods Posthoc analysis of a national …

Aims Acute heart failure (AHF) poses a major threat to hospitalized patients for its high
mortality rate and serious complications. The aim of this study is to determine whether …

Background Recent studies have shown an association between baseline arterial carbon
dioxide pressure (PaCO2) and outcomes in patients with acute respiratory distress …

BACKGROUND: Lung-protective ventilation (reduced tidal volume and limited plateau
pressure) may lead to CO2 retention. Data about the impact of hypercapnia in patients with …

Background: This study aimed to investigate the associations between dyscapnia,
ventilatory variables, and mortality. We hypothesized that the association between …

Background Previous studies found that high levels of ventilatory ratio (VR) were associated
with a poor prognosis due to worse ventilatory efficiency in acute respiratory distress …