Potentiation of paraquat toxicity by inhibition of the antioxidant defenses and protective effect of the natural antioxidant, 4-hydroxyisopthalic acid in Drosophila …

S Niveditha, T Shivanandappa - … and Physiology Part C: Toxicology & …, 2022 - Elsevier
Exposure to pesticides such as paraquat (PQ) is known to induce oxidative stress-mediated
damage, which is implicated in neurodegenerative diseases. The antioxidant enzymes are …

Piranhea trifoliata extracts ameliorate muscular decline in Drosophila melanogaster exposed to Paraquat

LP de Alencar, LL da Costa, DR Lisboa… - Archives of Insect …, 2023 - Wiley Online Library
In this study, we have demonstrated, for the first time, the muscular protective effects of
Piranhea trifoliata bark extract against Paraquat (PQ)‐induced oxidative stress in Drosophila …

Neuroprotective action of 4-Hydroxyisophthalic acid against paraquat-induced motor impairment involves amelioration of mitochondrial damage and …

S Niveditha, T Shivanandappa - Neurotoxicology, 2018 - Elsevier
Neurodegenerative disorders including Parkinson's disease (PD) are believed to be caused
by oxidative stress and mitochondrial dysfunction. Exposure to environmental agents such …

Alpha‐lipoic acid ameliorates tauopathy‐induced oxidative stress, apoptosis, and behavioral deficits through the balance of DIAP1/DrICE ratio and redox homeostasis …

E Zarini-Gakiye, N Sanadgol, K Parivar… - Metabolic Brain Disease, 2021 - Springer
Tauopathies belong to a heterogeneous class of neuronal diseases resulting in the
metabolic disturbance. A disulfide natural compound of Alpha-Lipoic acid (ALA) has shown …

Tribolium castaneum as a whole‐animal screening system for the detection and characterization of neuroprotective substances

A Brandt, G Joop, A Vilcinskas - Archives of insect biochemistry …, 2019 - Wiley Online Library
Parkinson's disease (PD) is a movement disorder caused by the progressive loss of
dopaminergic neurons. Natural antioxidants and plant extracts with neuroprotective …

Biochemical Impact of Carica Papaya (Pawpaw) leaves Extract and Ruzu Bitters on Hematology and Brain Histology in Sprague Dawley Rats

OAT Ebuehi, LO Ayobami… - Recent Progress in …, 2023 - lidsen.com
Plant-based products have been utilized for nutritional and medicinal purposes for decades.
Although the reported benefits of Carica papaya (Pawpaw) leave extract, its role in …

[PDF][PDF] In vitro callus induction and antioxidant potential of Decalepis hamiltonii (wight and arn)

TG Umesh - Int. J. Pharm. Sci, 2014 - academia.edu
Objective: To develop in vitro callus induction in nodal segments of Decalepis hamiltonii and
investigate the antioxidant potential of the callus. Methods: In this study, nodal segments of …

Senescence and oxidative stress toxicities induced by lamivudine and tenofovir in Drosophila melanogaster

WM Iorjiim, S Omale, MA Etuh, A Ubani… - Annales …, 2022 - Elsevier
Background Lamivudine and tenofovir disoproxil fumarate act against the replication of
hepatitis B and human immunodeficiency viruses via inhibition of the reverse transcriptase …

Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in …

VR Athira, T Shivanandappa… - Drug and Chemical …, 2022 - Taylor & Francis
Although, cyclophosphamide (CP) treatment is known to cause degeneration of the ovarian
follicular reserve, which may have a serious consequence of the onset of early reproductive …

Potential of whey protein as a nutritional intervention in alleviating manganese and paraquat-mediated oxidative stress in Apis mellifera meda

Z Khooshe-Bast, N Sahebzadeh, M Haddadi, A Khani - Apidologie, 2023 - Springer
The role of nutrition in alleviating the physiological disorders caused by toxicants in
honeybees is currently receiving considerable attention. This study aimed to determine …