Naturally Acquired Antibodies Specific for Plasmodium falciparum Reticulocyte-Binding Protein Homologue 5 Inhibit Parasite Growth and Predict Protection From …
TM Tran, A Ongoiba, J Coursen… - The Journal of …, 2014 - academic.oup.com
Background. Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) is a
blood-stage parasite protein essential for host erythrocyte invasion. PfRH5-specific …
blood-stage parasite protein essential for host erythrocyte invasion. PfRH5-specific …
Immunity to malaria in an era of declining malaria transmission
FJI Fowkes, P Boeuf, JG Beeson - Parasitology, 2016 - cambridge.org
With increasing malaria control and goals of malaria elimination, many endemic areas are
transitioning from high-to-low-to-no malaria transmission. Reductions in transmission will …
transitioning from high-to-low-to-no malaria transmission. Reductions in transmission will …
[HTML][HTML] IgG subclass staining in renal biopsies with membranous glomerulonephritis indicates subclass switch during disease progression
Recent breakthrough findings revealed that most patients with idiopathic (primary)
membranous glomerulonephritis have IgG4 antibodies to the phospholipase A2 receptor …
membranous glomerulonephritis have IgG4 antibodies to the phospholipase A2 receptor …
[HTML][HTML] Differential Patterns of IgG Subclass Responses to Plasmodium falciparum Antigens in Relation to Malaria Protection and RTS,S Vaccination
Naturally acquired immunity (NAI) to Plasmodium falciparum malaria is mainly mediated by
IgG antibodies but the subclasses, epitope targets and effector functions have not been …
IgG antibodies but the subclasses, epitope targets and effector functions have not been …
[HTML][HTML] Cohort study of the association of antibody levels to AMA1, MSP119, MSP3 and GLURP with protection from clinical malaria in Ghanaian children
Background Antigen-specific antibody-mediated immune responses play an important role
in natural protection against clinical malaria, but conflicting estimates of this association …
in natural protection against clinical malaria, but conflicting estimates of this association …
Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development
The study of antigenic targets of naturally-acquired immunity is essential to identify and
prioritize antigens for further functional characterization. We measured total IgG antibodies …
prioritize antigens for further functional characterization. We measured total IgG antibodies …
[HTML][HTML] Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases
Tissue inflammation results in the production of numerous reactive oxygen, nitrogen and
chlorine species, in addition to the products of lipid and sugar oxidation. Some of these …
chlorine species, in addition to the products of lipid and sugar oxidation. Some of these …
[HTML][HTML] Citrullinated and malondialdehyde-acetaldehyde modified fibrinogen activates macrophages and promotes an aggressive synovial fibroblast phenotype in …
N Aripova, MJ Duryee, BR England, CD Hunter… - Frontiers in …, 2023 - frontiersin.org
Objective Post-translational protein modifications with malondialdehyde-acetaldehyde
(MAA) and citrulline (CIT) are implicated in the pathogenesis of rheumatoid arthritis (RA) …
(MAA) and citrulline (CIT) are implicated in the pathogenesis of rheumatoid arthritis (RA) …
[HTML][HTML] Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure
Background Antibodies against merozoite antigens are key components of malaria
immunity. The naturally acquired antibody response to these antigens is generally …
immunity. The naturally acquired antibody response to these antigens is generally …
[HTML][HTML] The Quantity and Quality of African Children's IgG Responses to Merozoite Surface Antigens Reflect Protection against Plasmodium falciparum Malaria
D Courtin, M Oesterholt, H Huismans, K Kusi, J Milet… - PloS one, 2009 - journals.plos.org
Background Antibodies, particularly cytophilic IgG subclasses, with specificity for asexual
blood stage antigens of Plasmodium falciparum, are thought to play an important role in …
blood stage antigens of Plasmodium falciparum, are thought to play an important role in …