Reappraising the role of inflammation in heart failure

L Adamo, C Rocha-Resende, SD Prabhu… - Nature Reviews …, 2020 - nature.com
The observation that heart failure with reduced ejection fraction is associated with elevated
circulating levels of pro-inflammatory cytokines opened a new area of research that has …

Inflammation in human heart failure: major mediators and therapeutic targets

M Reina-Couto, P Pereira-Terra… - Frontiers in …, 2021 - frontiersin.org
Inflammation has been recognized as a major pathophysiological contributor to the entire
spectrum of human heart failure (HF), including HF with reduced ejection fraction, HF with …

Innate immunity and the failing heart: the cytokine hypothesis revisited

DL Mann - Circulation research, 2015 - Am Heart Assoc
Elevated levels of inflammatory mediators have been identified in patients with heart failure,
including heart failure with reduced and preserved ejection fraction, as well as acute …

Role of inflammation in heart failure

LF Shirazi, J Bissett, F Romeo, JL Mehta - Current atherosclerosis reports, 2017 - Springer
Abstract Purpose of Review This paper aims to discuss the interactions between
inflammatory cytokines, immune cells, and heart failure (HF). The association of heart failure …

Immune mechanisms in heart failure

Y Zhang, J Bauersachs… - European Journal of Heart …, 2017 - Wiley Online Library
Elevated levels of circulating pro‐inflammatory biomarkers in patients with both ischaemic
and non‐ischaemic heart failure (HF) correlate with disease severity and prognosis …

Biomarkers in heart failure

E Braunwald - New England Journal of Medicine, 2008 - Mass Medical Soc
Heart failure results not only from cardiac overload or injury but also from a complex
interplay among genetic, neurohormonal, inflammatory, and biochemical changes acting on …

Inflammatory cytokines in heart failure: mediators and markers

L Gullestad, T Ueland, LE Vinge, A Finsen, A Yndestad… - Cardiology, 2012 - karger.com
Evidence from both experimental and clinical trials indicates that inflammatory mediators are
of importance in the pathogenesis of chronic heart failure (HF) contributing to cardiac …

[HTML][HTML] Oxidative stress: New insights on the association of non-alcoholic fatty liver disease and atherosclerosis

L Polimeni, M Del Ben, F Baratta, L Perri… - World journal of …, 2015 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging
chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from …

Anti-TNF-α Compounds as a Treatment for Depression

S Uzzan, AN Azab - Molecules, 2021 - mdpi.com
Millions of people around the world suffer from psychiatric illnesses, causing unbearable
burden and immense distress to patients and their families. Accumulating evidence …

Cardiac cachexia: a systematic overview

S von Haehling, M Lainscak, J Springer… - Pharmacology & …, 2009 - Elsevier
Cardiac cachexia as a terminal stage of chronic heart failure carries a poor prognosis. The
definition of this clinical syndrome has been a matter of debate in recent years. This review …