Clinicians have long sought to characterize biological markers of neoplasia as objective
indicators of tumor presence, pathogenicity, and prognosis. Armed with data that correlate …

Background Lymph node metastasis (LNM) is frequent in papillary thyroid carcinoma (PTC)
and is associated with a poor prognosis. Unlike central LNM (CLNM), there are few studies …

Thyroid nodules are detected in up to 50 to 60% of healthy subjects. Most nodules do not
cause clinically significant symptoms, and as a result, the main challenge in their …

Abstract American Association of Clinical Endocrinologists, Associazione Medici
Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for …

Thyroid nodules are frequently found. Although they are often palpable, many are found
incidentally during unrelated radiographic studies. Ten to 15% of thyroid nodules represents …

AACE= American Association of Clinical Endocrinologists; AFTN= autonomously functioning
thyroid nodule; AME= Associazione Medici Endocrinologi; BEL= best evidence level; CNB …

Increasing evidence has experimentally proved the competitive endogenous RNA (ceRNA)
hypothesis that long non-coding RNA (lncRNA) can affect the expression of RNA targets by …

Objective: Many patients undergoing thyroidectomy for papillary thyroid carcinoma (PTC)
have subclinical nodal disease at the time of surgery. Prophylactic bilateral central neck …

Long noncoding RNAs (lncRNAs) have been proved to play important roles in cancer
biology. To understand their expression profile and potential functions in papillary thyroid …

Objectives This study aimed to develop a computed tomography (CT)-based radiomics
model to predict central lymph node metastases (CLNM) preoperatively in patients with …