Antiretrovirals to CCR5 CRISPR/Cas9 gene editing-A paradigm shift chasing an HIV cure
The evolution of drug-resistant viral strains and anatomical and cellular reservoirs of HIV
pose significant clinical challenges to antiretroviral therapy. CCR5 is a coreceptor critical for …
pose significant clinical challenges to antiretroviral therapy. CCR5 is a coreceptor critical for …
Effect of graft-versus-host disease on post-transplantation outcomes following single cord blood transplantation compared with haploidentical transplantation with post …
T Konuma, K Matsuda, Y Shimomura, S Tanoue… - … and Cellular Therapy, 2023 - Elsevier
The possibility that HLA mismatches could reduce relapse after alternative HLA-mismatched
allogeneic hematopoietic cell transplantation (HCT) is an attractive concept for treating acute …
allogeneic hematopoietic cell transplantation (HCT) is an attractive concept for treating acute …
The impact of omidubicel on immune reconstitution and infections in cord blood transplant patients
H De Sa, RT Maziarz, AP Gandhi - Expert Opinion on Biological …, 2024 - Taylor & Francis
Introduction The success of an allogeneic hematopoietic stem cell transplantation (alloHCT)
is measured by cure from the underlying malignancy, immune reconstitution (IR), and …
is measured by cure from the underlying malignancy, immune reconstitution (IR), and …
Long-term outcome of second allogeneic hematopoietic stem cell transplantation (HSCT2) for primary graft failure in patients with acute leukemia in remission: A study …
Second transplantation (HSCT2) is a potential treatment for primary graft failure (pGF). We
assessed the outcome of HSCT2, performed between 2000 and 2021, for pGF in 243 …
assessed the outcome of HSCT2, performed between 2000 and 2021, for pGF in 243 …
Feasibility and safety of the discontinuation of systemic immunosuppressive treatment after single-unit cord blood transplantation in adults
T Konuma, M Monna-Oiwa, S Kato, M Isobe… - Bone Marrow …, 2024 - nature.com
We retrospectively evaluated the incidence, factors, and clinical outcomes of the
discontinuation of immunosuppressive treatment (IST) after single-unit unrelated cord blood …
discontinuation of immunosuppressive treatment (IST) after single-unit unrelated cord blood …
Haploidentical transplantation in primary refractory/relapsed secondary versus de novo AML: from the ALWP/EBMT
We compared the outcomes of haploidentical stem cell transplantation (HaploHSCT) with
post-transplant cyclophosphamide (PTCy) in 719 patients (pts) with primary refractory …
post-transplant cyclophosphamide (PTCy) in 719 patients (pts) with primary refractory …
Association between human herpesvirus-6 encephalitis and antiviral prophylaxis after allogeneic hematopoietic stem cell transplantation in the letermovir era
T Terao, K Matsuoka, S Fuji, S Kawamura… - Bone Marrow …, 2024 - nature.com
The impact of letermovir (LTV)—an anti-cytomegalovirus (CMV) drug—on human
herpesvirus-6 (HHV-6) encephalitis is unclear. We hypothesized that LTV prophylaxis may …
herpesvirus-6 (HHV-6) encephalitis is unclear. We hypothesized that LTV prophylaxis may …
Fifty years of BMT: risk stratification, donor matching, and stem cell collection for transplantation
A Salhotra, S Yuan, H Ali - Frontiers in Oncology, 2023 - frontiersin.org
In this review, we discuss recipient risk assessment for allo-HCT regarding comorbidities
present at baseline to predict non relapse mortality. We further reviewed the incorporation of …
present at baseline to predict non relapse mortality. We further reviewed the incorporation of …
[PDF][PDF] Conditioning
A Shimoni, V Radici, A Nagler - The EBMT Handbook …, 2024 - library.oapen.org
Hematopoietic cell transplantation (HCT) is a potentially curative therapeutic procedure in a
broad range of malignant and nonmalignant hematological disorders. Conditioning is the …
broad range of malignant and nonmalignant hematological disorders. Conditioning is the …
[PDF][PDF] AML in Adults
J Versluis, JJ Cornelissen, C Craddock… - The EBMT Handbook …, 2024 - library.oapen.org
Allo-HCT plays an increasingly important role in the management of AML in adults (Dohner
et al. 2022). The advent of RIC regimens coupled with increased donor availability has …
et al. 2022). The advent of RIC regimens coupled with increased donor availability has …