On-chip recapitulation of the tumor microenvironment: A decade of progress
One of the hurdles to the development of new anticancer therapies is the lack of in vitro
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …
[HTML][HTML] Toward innovative approaches for exploring the mechanically regulated tumor-immune microenvironment
M Kalli, T Stylianopoulos - APL bioengineering, 2024 - pubs.aip.org
Within the complex tumor microenvironment, cells experience mechanical cues—such as
extracellular matrix stiffening and elevation of solid stress, interstitial fluid pressure, and fluid …
extracellular matrix stiffening and elevation of solid stress, interstitial fluid pressure, and fluid …
Sensitive Electrochemical Detection of Carcinoembryonic Antigen Based on Biofunctionalized Nanochannel Modified Carbonaceous Electrode
Y Zhou, H Wang, F Xi, C Lu - Molecules, 2024 - mdpi.com
The convenient construction of carbon-based electrochemical immunosensors with high
performance is highly desirable for the efficient detection of tumor biomarkers. In this work …
performance is highly desirable for the efficient detection of tumor biomarkers. In this work …
Tuneable hydrogel patterns in pillarless microfluidic devices
C Olaizola-Rodrigo, S Palma-Florez, T Ranđelović… - Lab on a Chip, 2024 - pubs.rsc.org
Organ-on-chip (OOC) technology has recently emerged as a powerful tool to mimic
physiological or pathophysiological conditions through cell culture in microfluidic devices …
physiological or pathophysiological conditions through cell culture in microfluidic devices …
Tumor-on-chip platforms for Breast Cancer Continuum Concept modeling
Our previous article entitled" Proteomics and its applications in breast cancer", proposed a
Breast Cancer Continuum Concept (BCCC), including a Breast Cancer Cell Continuum …
Breast Cancer Continuum Concept (BCCC), including a Breast Cancer Cell Continuum …
In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges
MM Rahman, G Wells, JK Rantala… - Expert Review of …, 2024 - Taylor & Francis
Introduction Immunotherapies have revolutionized cancer treatment, but often fail to produce
desirable therapeutic outcomes in all patients. Due to the inter-patient heterogeneity and …
desirable therapeutic outcomes in all patients. Due to the inter-patient heterogeneity and …
An Overview of Advancements and Technologies in Vascularization Strategies for Tumor‐On‐A‐Chip Models
Vascularized tumor on a chip (VToC) entail emulating intricate microvascular networks like
those observed in tumors through microfluidic devices, which are meticulously designed to …
those observed in tumors through microfluidic devices, which are meticulously designed to …
[HTML][HTML] 循环肿瘤细胞检测在临床癌症的应用进展
张宁伟， 任宾 - Advances in Clinical Medicine, 2023 - hanspub.org
随着精准医学的发展, 液体活检技术开始在临床上广泛应用. 循环肿瘤细胞(CTC)
是从原发性肿瘤脱离进入外周血液循环的肿瘤细胞, 经过一系列迁移, 黏附和聚集后形成新的 …
是从原发性肿瘤脱离进入外周血液循环的肿瘤细胞, 经过一系列迁移, 黏附和聚集后形成新的 …
Microfluidic chips as drug screening platforms
I Kim, J Kwon, J Rhyou, JS Jeon - JMST Advances, 2024 - Springer
The selection of a disease model is a crucial factor in drug screening. Research based on
microfluidic chips utilizes various chip designs and cell culture methods to overcome the …
microfluidic chips utilizes various chip designs and cell culture methods to overcome the …
Toward innovative approaches for exploring the mechanically regulated tumor-immune microenvironment
M Kallia, T Stylianopoulosa - europepmc.org
Within the complex tumor microenvironment, cells experience mechanical cues—such as
extracellular matrix stiffening and elevation of solid stress, interstitial fluid pressure, and fluid …
extracellular matrix stiffening and elevation of solid stress, interstitial fluid pressure, and fluid …