Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent
reperfusion of the brain following resuscitation. In those who are admitted to intensive care …

The vast majority of cerebral stroke cases are caused by transient or permanent occlusion of
a cerebral blood vessel (“ischemic stroke”) eventually leading to brain infarction. The final …

The mammalian retina provides an excellent opportunity to study glia–neuron interactions
and the interactions of glia with blood vessels. Three main types of glial cells are found in …

The no-reflow phenomenon refers to the observation that when an organ is made ischemic
by occlusion of a large artery supplying it, restoration of patency in that artery does not …

The blood-brain barrier (BBB) is formed by the endothelial cells of cerebral microvessels,
providing a dynamic interface between the peripheral circulation and the central nervous …

Objective: Epinephrine has been the primary drug for cardiopulmonary resuscitation (CPR)
for more than a century. The therapeutic rationale was to restore threshold levels of …

Perinatal brain damage in the mature fetus is usually brought about by severe intrauterine
asphyxia following an acute reduction of the uterine or umbilical circulation. The areas most …

OBJECTIVE:: LUCAS is a new device for mechanical compression and decompression of
the chest during cardiopulmonary resuscitation (CPR). The aim of this study was to compare …

Objective. Free radical-induced postasphyxial reperfusion injury has been recognized as an
important cause of brain tissue damage. We investigated the effect of high-dose allopurinol …

Objective Successful resuscitation of the brain requires complete microcirculatory
reperfusion, which, however, may be impaired by activation of blood coagulation after …