Abstract The National Center for Biotechnology Information (NCBI) produces a variety of
online information resources for biology, including the GenBank® nucleic acid sequence …

The assembly of single-amplified genomes (SAGs) and metagenome-assembled genomes
(MAGs) has led to a surge in genome-based discoveries of members affiliated with Archaea …

Rfam is a database of RNA families where each of the 3444 families is represented by a
multiple sequence alignment of known RNA sequences and a covariance model that can be …

Comprehensive, high-quality reference genomes are required for functional characterization
and taxonomic assignment of the human gut microbiota. We present the Unified Human …

Reconstruction of target genomes from sequence data produced by instruments that are
agnostic as to the species-of-origin may be confounded by contaminant DNA. Whether …

Cytokines are critical for intercellular communication in human health and disease, but the
investigation of cytokine signaling activity has remained challenging due to the short half …

Abstract The International Nucleotide Sequence Database Collaboration (INSDC;
http://www. insdc. org/) has been the core infrastructure for collecting and providing …

OMA is an established resource to elucidate evolutionary relationships among genes from
currently 2326 genomes covering all domains of life. OMA provides pairwise and groupwise …

Abstract The European Nucleotide Archive (ENA; https://www. ebi. ac. uk/ena), provided by
the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) …

Abstract The European Variation Archive (EVA; https://www. ebi. ac. uk/eva/) is a resource
for sharing all types of genetic variation data (SNPs, indels, and structural variants) for all …