Cancer active targeting by nanoparticles: a comprehensive review of literature

R Bazak, M Houri, S El Achy, S Kamel… - Journal of cancer research …, 2015 - Springer
Purpose Cancer is one of the leading causes of death, and thus, the scientific community
has but great efforts to improve cancer management. Among the major challenges in cancer …

Sensors and biosensors based on magnetic nanoparticles

TAP Rocha-Santos - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
Magnetic nanoparticles (MNPs) have attracted a growing interest in the development and
fabrication of sensors and biosensors for several applications. MNPs can be integrated into …

Insights on magnetic spinel ferrites for targeted drug delivery and hyperthermia applications

MIA Abdel Maksoud, MM Ghobashy… - Nanotechnology …, 2022 - degruyter.com
Magnetic spinel ferrite nanoparticles (SFNPs) attract high scientific attention from
researchers due to their broad area for biomedicine applications, comprising cancer …

Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer

F Chen, K Ma, B Madajewski, L Zhuang… - Nature …, 2018 - nature.com
Controlling the biodistribution of nanoparticles upon intravenous injection is the key to
achieving target specificity. One of the impediments in nanoparticle-based tumor targeting is …

Emerging tumor spheroids technologies for 3D in vitro cancer modeling

T Rodrigues, B Kundu, J Silva-Correia… - Pharmacology & …, 2018 - Elsevier
Cancer is a leading cause of mortality and morbidity worldwide. Around 90% of deaths are
caused by metastasis and just 10% by primary tumor. The advancement of treatment …

Magnetic iron oxide nanoparticles as drug carriers: Preparation, conjugation and delivery

K El-Boubbou - Nanomedicine, 2018 - Taylor & Francis
Magnetic nanoparticles (MNPs), particularly made of iron oxides, have been extensively
studied as diagnostic imaging agents and therapeutic delivery vehicles. In this review …

Nano-biosensor for highly sensitive detection of HER2 positive breast cancer

R Salahandish, A Ghaffarinejad, SM Naghib… - Biosensors and …, 2018 - Elsevier
Nanocomposite materials have provided a wide range of conductivity, sensitivity, selectivity
and linear response for electrochemical biosensors. However, the detection of rare cells at …

Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) as platform for the targeted multimodal tumor therapy

C Janko, T Ratschker, K Nguyen, L Zschiesche… - Frontiers in …, 2019 - frontiersin.org
Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …

[HTML][HTML] Screening for ovarian cancer: imaging challenges and opportunities for improvement

KB Mathieu, DG Bedi, SL Thrower… - … in obstetrics & …, 2018 - ncbi.nlm.nih.gov
Abstract The United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
recently reported a reduction in the average overall mortality among ovarian cancer patients …

Applications of nanoparticle-antibody conjugates in immunoassays and tumor imaging

X Lin, A O'Reilly Beringhs, X Lu - The AAPS journal, 2021 - Springer
Modern diagnostic technologies rely on both in vitro and in vivo modalities to provide a
complete understanding of the clinical state of a patient. Nanoparticle-antibody conjugates …