Chemometrics-assisted solid-state characterization of pharmaceutically relevant materials. Polymorphic substances
NL Calvo, RM Maggio, TS Kaufman - Journal of pharmaceutical and …, 2018 - Elsevier
Current regulations command to properly characterize pharmaceutically relevant solid
systems. Chemometrics comprise a range of valuable tools, suitable to process large …
systems. Chemometrics comprise a range of valuable tools, suitable to process large …
Thermoanalytical techniques of nanomaterials
Designing and fabrication of materials with good thermal characteristics is very important for
multifunctional applications of nanomaterials. Thermal analysis is a group of techniques that …
multifunctional applications of nanomaterials. Thermal analysis is a group of techniques that …
[HTML][HTML] Agglomerated novel spray-dried lactose-leucine tailored as a carrier to enhance the aerosolization performance of salbutamol sulfate from DPI formulations
C Molina, W Kaialy, Q Chen, D Commandeur… - Drug delivery and …, 2018 - Springer
Spray-drying allows to modify the physicochemical/mechanical properties of particles along
with their morphology. In the present study, L-leucine with varying concentrations (0.1, 0.5, 1 …
with their morphology. In the present study, L-leucine with varying concentrations (0.1, 0.5, 1 …
Understanding compression-induced amorphization of crystalline posaconazole
Process-induced phase transformations (PIPTs) of active pharmaceutical ingredients (APIs)
can alter APIs' physicochemical properties and impact performance of pharmaceutical drug …
can alter APIs' physicochemical properties and impact performance of pharmaceutical drug …
Simultaneous improvement of solubility and permeability by fabricating binary glassy materials of Talinolol with Naringin: Solid state characterization, in-vivo in-situ …
A Teja, PB Musmade, AB Khade, SJ Dengale - European Journal of …, 2015 - Elsevier
The aim of the current study was to prepare binary amorphous forms of Talinolol (TLN) by
using Naringin (NRG) as a stabilizing agent. The secondary objective of this study was to …
using Naringin (NRG) as a stabilizing agent. The secondary objective of this study was to …
Development, characterisation and nasal deposition of melatonin-loaded pectin/hypromellose microspheres
L Nižić, J Potaś, K Winnicka, M Szekalska, I Erak… - European journal of …, 2020 - Elsevier
In this study, we present the development of spray-dried pectin/hypromellose microspheres
as efficient melatonin carrier for targeted nasal delivery. Different pectin to hypromellose …
as efficient melatonin carrier for targeted nasal delivery. Different pectin to hypromellose …
A solid-state chemist's view of the crystal polymorphism of organic compounds
A Gavezzotti - Journal of pharmaceutical sciences, 2007 - Elsevier
In a survey of some structural and energetic aspects of crystal polymorphism, definitions are
proposed, and a method for generating an unequivocal fingerprint of the cohesive pattern of …
proposed, and a method for generating an unequivocal fingerprint of the cohesive pattern of …
Transmission low-frequency Raman spectroscopy for quantification of crystalline polymorphs in pharmaceutical tablets
The purpose of this study was to quantify polymorphs of active pharmaceutical ingredients in
pharmaceutical tablets using a novel transmission low-frequency Raman spectroscopy …
pharmaceutical tablets using a novel transmission low-frequency Raman spectroscopy …
Particle engineering of needle shaped crystals by wet milling and temperature cycling: Optimisation for roller compaction
D Wilson, M Bunker, D Milne, A Jawor-Baczynska… - Powder technology, 2018 - Elsevier
Purpose The purpose of this work is to demonstrate a process for the alteration of the shape
of needle shaped crystals of an active pharmaceutical ingredient (API) using a combination …
of needle shaped crystals of an active pharmaceutical ingredient (API) using a combination …
Eudragit RS 100 microparticles containing 2-hydroxypropyl-β-cyclodextrin and glutathione: Physicochemical characterization, drug release and transport studies
A Trapani, V Laquintana, N Denora, A Lopedota… - European journal of …, 2007 - Elsevier
The aim of this study was to encapsulate glutathione (GSH) alone or in combination with
hydroxypropyl-β-cyclodextrin (HP-β-CD) in Eudragit RS 100 microparticles (MPs), and to …
hydroxypropyl-β-cyclodextrin (HP-β-CD) in Eudragit RS 100 microparticles (MPs), and to …