On iron metabolism and its regulation

ACS Vogt, T Arsiwala, M Mohsen, M Vogel… - International journal of …, 2021 - mdpi.com
Iron is a critical metal for several vital biological processes. Most of the body's iron is bound
to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by …

Iron deficiency anemia: efficacy and limitations of nutritional and comprehensive mitigation strategies

SB Kumar, SR Arnipalli, P Mehta, S Carrau… - Nutrients, 2022 - mdpi.com
Iron deficiency anemia (IDA) has reached epidemic proportions in developing countries and
has become a major global public health problem, affecting mainly 0–5-year-old children …

[HTML][HTML] Iron deficiency anemia in children residing in high and low-income countries: risk factors, prevention, diagnosis and therapy

E Mantadakis, E Chatzimichael… - Mediterranean journal of …, 2020 - ncbi.nlm.nih.gov
Iron deficiency and iron-deficiency anemia (IDA) affects approximately two billion people
worldwide, and most of them reside in low-and middle-income countries. In these nations …

The role of iron in cancer progression

Q Guo, L Li, S Hou, Z Yuan, C Li, W Zhang… - Frontiers in …, 2021 - frontiersin.org
Iron is an essential trace element for the human body, and its deficiency or excess can
induce a variety of biological processes. Plenty of evidences have shown that iron …

SARS-CoV-2 infects red blood cell progenitors and dysregulates hemoglobin and iron metabolism

R Kronstein-Wiedemann, M Stadtmüller… - Stem cell reviews and …, 2022 - Springer
Background SARS-CoV-2 infection causes acute respiratory distress, which may progress to
multiorgan failure and death. Severe COVID-19 disease is accompanied by reduced …

Iron metabolism in cardiovascular disease: physiology, mechanisms, and therapeutic targets

KT Sawicki, A De Jesus, H Ardehali - Circulation research, 2023 - Am Heart Assoc
The cardiovascular system requires iron to maintain its high energy demands and metabolic
activity. Iron plays a critical role in oxygen transport and storage, mitochondrial function, and …

Insight into crosstalk between ferroptosis and necroptosis: novel therapeutics in ischemic stroke

Y Zhou, J Liao, Z Mei, X Liu, J Ge - Oxidative Medicine and …, 2021 - Wiley Online Library
Ferroptosis is a nonapoptotic form of cell death characterized by iron‐dependent
accumulation of lipid hydroperoxides to lethal levels. Necroptosis, an alternative form of …

Emerging roles of the iron chelators in inflammation

A Di Paola, C Tortora, M Argenziano… - International Journal of …, 2022 - mdpi.com
Iron is a crucial element for mammalian cells, considering its intervention in several
physiologic processes. Its homeostasis is finely regulated, and its alteration could be …

A review of nutrients and compounds, which promote or inhibit intestinal iron absorption: making a platform for dietary measures that can reduce iron uptake in …

NT Milman - Journal of Nutrition and Metabolism, 2020 - Wiley Online Library
Objective. To provide an overview of nutrients and compounds, which influence human
intestinal iron absorption, thereby making a platform for elaboration of dietary …

Recent advances in iron encapsulation and its application in food fortification

D Dehnad, B Ghorani, B Emadzadeh… - Critical Reviews in …, 2023 - Taylor & Francis
Iron (Fe) is an important element for our body since it takes part in a huge variety of
metabolic processes. However, the direct incorporation of Fe into food fortification causes a …