Protein and peptide drugs hold great promise as therapeutic agents. However, many are
degraded by proteolytic enzymes, can be rapidly cleared by the kidneys, generate …

Interferons are cytokines that have antiviral, antiproliferative and immunomodulatory effects.
Because of these important properties, in the past two decades, major research efforts have …

Liver Disease (LD) is the main cause of death worldwide, affecting a large number of
people. A variety of factors affect the liver, resulting in this disease. The diagnosis of this …

Introduction: Over 2 million adults in the United States have hepatitis C virus (HCV) infection,
and it contributes to approximately 14,000 deaths a year. Eight to 12 weeks of highly …

These guidelines for the treatment of persons who have or are at risk for sexually transmitted
infections (STIs) were updated by CDC after consultation with professionals knowledgeable …

Background The hepatitis C virus (HCV) is a major public health problem and a leading
cause of chronic liver disease. 5 An estimated 180 million people are infected worldwide. 6 …

Importance Infection with hepatitis C virus (HCV) is a major cause of morbidity and mortality
in the United States, and incidence has increased rapidly in recent years, likely owing to …

Current and Future Therapies for Hepatitis C Virus Infection | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

Much controversy surrounds the issue of the natural history of hepatitis C virus (HCV)
infection. Many authorities view the disease as inexorably progressive with a high …

The safety and efficacy of protein therapeutics are limited by three interrelated
pharmaceutical issues, in vitro and in vivo instability, immunogenicity and shorter half-lives …