Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments

F Lemaitre, C Solas, M Grégoire… - Fundamental & …, 2020 - Wiley Online Library
Patients with COVID‐19 are sometimes already being treated for one or more other chronic
conditions, especially if they are elderly. Introducing a treatment against COVID‐19, either …

[HTML][HTML] The inhibitory and inducing effects of ritonavir on hepatic and intestinal CYP3A and other drug-handling proteins

NHC Loos, JH Beijnen, AH Schinkel - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ritonavir, originally developed as HIV protease inhibitor, is widely used as a booster in
several HIV pharmacotherapy regimens and more recently in Covid-19 treatment (eg …

Lopinavir-ritonavir treatment for COVID-19 infection in intensive care unit: risk of bradycardia

C Beyls, N Martin, A Hermida… - Circulation …, 2020 - Am Heart Assoc
At the start of the coronavirus disease 2019 (COVID-19) outbreak in Europe, specific
antiviral treatments were based on previous experience with SARS-Cov-1 (severe acute …

Lopinavir-ritonavir in SARS-CoV-2 infection and drug-drug interactions with cardioactive medications

S Agarwal, SK Agarwal - Cardiovascular drugs and therapy, 2021 - Springer
Lopinavir-ritonavir combination is being used for the treatment of SARS-CoV-2 infection. A
low dose of ritonavir is added to other protease inhibitors to take advantage of potent …

A Double-Edged Sword—Cardiovascular Concerns of Potential Anti-COVID-19 Drugs

WL Yu, HS Toh, CT Liao, WT Chang - Cardiovascular Drugs and Therapy, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic infection caused by Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). COVID-19 significantly affects …

Safety and efficacy of antiviral drugs for the treatment of COVID-19: a systematic review

Z Nie, T Sun, F Zhao - Infection and Drug Resistance, 2022 - Taylor & Francis
Objective To investigate the efficacy and safety of antiviral drugs in the treatment of
coronavirus disease 2019 (COVID-19). Methods All clinical trials of antiviral drug treatment …

Managing drug interactions in HIV-infected adults with comorbid illness

CA Hughes, A Tseng, R Cooper - Cmaj, 2015 - Can Med Assoc
With the introduction of combination antiretroviral therapy, HIV-1 infection is now considered
a treatable chronic infectious disease. Modern combination antiretroviral therapy consists of …

Repurpose but also (nano)-reformulate! The potential role of nanomedicine in the battle against SARS-CoV2

SN Tammam, S El Safy, S Ramadan, S Arjune… - Journal of Controlled …, 2021 - Elsevier
Abstract The coronavirus disease-19 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV2) has taken the world by surprise. To date, a …

Spontaneous reported cardiotoxicity induced by lopinavir/ritonavir in COVID-19. An alleged past-resolved problem

A Fresse, D Viard, S Romani, A Gérard… - International Journal of …, 2021 - Elsevier
The antiretroviral drug lopinavir/ritonavir has been recently repurposed for the treatment of
COVID-19. Its empirical use has been associated with multiple cardiac adverse reactions …

A review of drug-drug interactions in older HIV-infected patients

A Chary, NN Nguyen, K Maiton… - Expert Review of Clinical …, 2017 - Taylor & Francis
Introduction: The number of older HIV-infected people is growing due to increasing life
expectancies resulting from the use of antiretroviral therapy (ART). Both HIV and aging …