The genetics of kidney stone disease and nephrocalcinosis

P Singh, PC Harris, DJ Sas, JC Lieske - Nature Reviews Nephrology, 2022 - nature.com
Kidney stones (also known as urinary stones or nephrolithiasis) are highly prevalent,
affecting approximately 10% of adults worldwide, and the incidence of stone disease is …

Skeletal and extraskeletal disorders of biomineralization

MT Collins, G Marcucci, HJ Anders, G Beltrami… - Nature Reviews …, 2022 - nature.com
The physiological process of biomineralization is complex and deviation from it leads to a
variety of diseases. Progress in the past 10 years has enhanced understanding of the …

Protective cellular mechanism of estrogen against kidney stone formation: a proteomics approach and functional validation

P Peerapen, V Thongboonkerd - Proteomics, 2019 - Wiley Online Library
Females have less incidence/prevalence of kidney stone disease than males. Estrogen thus
may serve as the protective factor but with unclear mechanism. This study explores cellular …

[HTML][HTML] Meta-data analysis of kidney stone disease highlights ATP1A1 involvement in renal crystal formation

Y Li, X Lu, Z Yu, H Wang, B Gao - Redox Biology, 2023 - Elsevier
Nephrolithiasis is a complicated disease affected by various environmental and genetic
factors. Crystal-cell adhesion is a critical initiation process during kidney stone formation …

Membrane transport proteins in osteoclasts: the ins and outs

ABP Ribet, PY Ng, NJ Pavlos - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
During bone resorption, the osteoclast must sustain an extraordinarily low pH environment,
withstand immense ionic pressures, and coordinate nutrient and waste exchange across its …

Animal models of naturally occurring stone disease

A Alford, E Furrow, M Borofsky, J Lulich - Nature Reviews Urology, 2020 - nature.com
The prevalence of urolithiasis in humans is increasing worldwide; however, non-surgical
treatment and prevention options remain limited despite decades of investigation. Most …

Risk factors for the comorbidity of osteoporosis/osteopenia and kidney stones: a cross-sectional study

Z Zhu, M Liu, Y Zhang, J Wu, M Gao, T Lei… - Archives of …, 2023 - Springer
Low femoral neck bone mineral density (BMD) was associated with the increased risk of
kidney stones. Low dietary magnesium intake and increased serum alkaline phosphatase …

Tight junction and kidney stone disease

P Rungrasameviriya, A Santilinon, P Atichartsintop… - Tissue …, 2024 - Taylor & Francis
Defects of tight junction (TJ) are involved in many diseases related to epithelial cell
functions, including kidney stone disease (KSD), which is a common disease affecting …

[HTML][HTML] Intestinal dysbacteriosis leads to kidney stone disease

E Zhao, W Zhang, B Geng, B You… - Molecular …, 2021 - spandidos-publications.com
The formation and physicochemical properties of kidney stones (KSs) are closely associated
with diet. In view of the differences in ethnicity and dietary composition between Chinese …

Genetic polymorphisms and kidney stones around the globe: a systematic review and meta-analysis

A Mohammadi, AN Shabestari, LZ Baghdadabad… - Frontiers in …, 2022 - frontiersin.org
Objective: This study explores associations between recurrent kidney stones and genetic
polymorphisms. Methods: Meta-analysis of polymorphisms in renal stone cases versus …