Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas …

JR Tait, D Anderson, RL Nation, DJ Creek… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Extracellular bacterial metabolites have potential as markers of bacterial growth and
resistance emergence but have not been evaluated in dynamic in vitro studies. We …

[HTML][HTML] Synergistic effects of inhaled aztreonam plus tobramycin on hypermutable cystic fibrosis Pseudomonas aeruginosa isolates in a dynamic biofilm model …

SKJ Breen, M Harper, C López-Causapé… - International journal of …, 2024 - Elsevier
Abstract Objective Hypermutable Pseudomonas aeruginosa strains are highly prevalent in
chronic lung infections of patients with cystic fibrosis (CF). Acute exacerbations of these …

Lytic transglycosylase Slt of Pseudomonas aeruginosa as a periplasmic hub protein

LF Avila‐Cobian, S De Benedetti, H Hoshino… - Protein …, 2024 - Wiley Online Library
Peptidoglycan is a major constituent of the bacterial cell wall. Its integrity as a polymeric
edifice is critical for bacterial survival and, as such, it is a preeminent target for antibiotics …