Suicidal behavior across a broad range of psychiatric disorders
YE Xu, DA Barron, K Sudol, S Zisook… - Molecular …, 2023 - nature.com
Suicide is a leading cause of death worldwide. In 2020, some 12.2 million Americans
seriously contemplated suicide, 3.2 million planned suicide attempts, and 1.2 million …
seriously contemplated suicide, 3.2 million planned suicide attempts, and 1.2 million …
Plasticity of synapses and reward circuit function in the genesis and treatment of depression
SM Thompson - Neuropsychopharmacology, 2023 - nature.com
What changes in brain function cause the debilitating symptoms of depression? Can we use
the answers to this question to invent more effective, faster acting antidepressant drug …
the answers to this question to invent more effective, faster acting antidepressant drug …
GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors
AR Docherty, N Mullins… - American journal of …, 2023 - Am Psychiatric Assoc
Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-
scale genome-wide association studies (GWASs) recently discovered and cross-validated …
scale genome-wide association studies (GWASs) recently discovered and cross-validated …
Genome-wide association study meta-analysis of suicide death and suicidal behavior
Suicide is a worldwide health crisis. We aimed to identify genetic risk variants associated
with suicide death and suicidal behavior. Meta-analysis for suicide death was performed …
with suicide death and suicidal behavior. Meta-analysis for suicide death was performed …
Identification of novel, replicable genetic risk loci for suicidal thoughts and behaviors among US military veterans
NA Kimbrel, AE Ashley-Koch, XJ Qin… - JAMA …, 2023 - jamanetwork.com
Importance Suicide is a leading cause of death; however, the molecular genetic basis of
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …
Biological factors underpinning suicidal behaviour: an update
Suicide, a global health burden, represents the 17th leading cause of death worldwide
(1.3%), but the 4th among young people aged between 15 and 29 years of age, according to …
(1.3%), but the 4th among young people aged between 15 and 29 years of age, according to …
Genetics and epigenetics of self‐injurious thoughts and behaviors: Systematic review of the suicide literature and methodological considerations
Suicide is a multifaceted and poorly understood clinical outcome, and there is an urgent
need to advance research on its phenomenology and etiology. Epidemiological studies …
need to advance research on its phenomenology and etiology. Epidemiological studies …
[HTML][HTML] How to save a life: From neurobiological underpinnings to psychopharmacotherapies in the prevention of suicide
The impact of suicide on our societies, mental healthcare, and public health is beyond
questionable. Every year approximately 700 000 lives are lost due to suicide around the …
questionable. Every year approximately 700 000 lives are lost due to suicide around the …
Developing and implementing predictive models in a learning healthcare system: traditional and artificial intelligence approaches in the Veterans Health …
D Atkins, CA Makridis, G Alterovitz… - Annual Review of …, 2022 - annualreviews.org
Predicting clinical risk is an important part of healthcare and can inform decisions about
treatments, preventive interventions, and provision of extra services. The field of predictive …
treatments, preventive interventions, and provision of extra services. The field of predictive …
Large epigenome-wide association study identifies multiple novel differentially methylated CpG sites associated with suicidal thoughts and behaviors in veterans
NA Kimbrel, ME Garrett, MK Evans, C Mellows… - Frontiers in …, 2023 - frontiersin.org
Introduction The US suicide mortality rate has steadily increased during the past two
decades, particularly among military veterans; however, the epigenetic basis of suicidal …
decades, particularly among military veterans; however, the epigenetic basis of suicidal …