Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study

A Sud, B Torr, ME Jones, J Broggio, S Scott… - The Lancet …, 2020 - thelancet.com
Background During the COVID-19 lockdown, referrals via the 2-week-wait urgent pathway
for suspected cancer in England, UK, are reported to have decreased by up to 84%. We …

Mixture cure models in oncology: a tutorial and practical guidance

F Felizzi, N Paracha, J Pöhlmann, J Ray - PharmacoEconomics-open, 2021 - Springer
Novel cancer therapies are associated with survival patterns that differ from established
therapies, which may include survival curves that plateau after a certain follow-up time point …

The current application of the Royston-Parmar model for prognostic modeling in health research: a scoping review

R Ng, K Kornas, R Sutradhar, WP Wodchis… - … and prognostic research, 2018 - Springer
Background Prognostic models incorporating survival analysis predict the risk (ie,
probability) of experiencing a future event over a specific time period. In 2002, Royston and …

[图书][B] Cure models: methods, applications, and implementation

Y Peng, B Yu - 2021 - taylorfrancis.com
Cure Models: Methods, Applications and Implementation is the first book in the last 25 years
that provides a comprehensive and systematic introduction to the basics of modern cure …

Cancer cure for 32 cancer types: results from the EUROCARE-5 study

L Dal Maso, C Panato, A Tavilla… - International Journal …, 2020 - academic.oup.com
Background Few studies have estimated the probability of being cured for cancer patients.
This study aims to estimate population-based indicators of cancer cure in Europe by type …

Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study

C Loveday, A Sud, ME Jones, J Broggio, S Scott… - Gut, 2021 - gut.bmj.com
Objective To evaluate the impact of faecal immunochemical testing (FIT) prioritisation to
mitigate the impact of delays in the colorectal cancer (CRC) urgent diagnostic (2-week-wait …

The use of restricted cubic splines to approximate complex hazard functions in the analysis of time-to-event data: a simulation study

MJ Rutherford, MJ Crowther… - Journal of Statistical …, 2015 - Taylor & Francis
If interest lies in reporting absolute measures of risk from time-to-event data then obtaining
an appropriate approximation to the shape of the underlying hazard function is vital. It has …

Estimating the loss in expectation of life due to cancer using flexible parametric survival models

TML Andersson, PW Dickman, S Eloranta… - Statistics in …, 2013 - Wiley Online Library
A useful summary measure for survival data is the expectation of life, which is calculated by
obtaining the area under a survival curve. The loss in expectation of life due to a certain type …

[PDF][PDF] Nice dsu technical support document 21: Flexible methods for survival analysis

MJ Rutherford, PC Lambert, MJ Sweeting… - Decision Support Unit …, 2020 - sheffield.ac.uk
Survival analysis modelling approaches are often required to capture the survival functions
seen in clinical trial data and to further extrapolate to estimate lifetime benefits in economic …

Conditional survival and cure of patients with colon or rectal cancer: a population-based study

SM Qaderi, PW Dickman, JHW de Wilt… - Journal of the national …, 2020 - jnccn.org
Background: The increasing number of colorectal cancer (CRC) survivors need survival
estimates that account for the time already survived. The aim of this population-based study …