[HTML][HTML] Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases

J Zhu, S Wang, D Yang, W Xu, H Qian - Journal of Nanobiotechnology, 2023 - Springer
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …

Innovations in the treatment of dystrophic epidermolysis bullosa (DEB): current landscape and prospects

PC Hou, N Del Agua, SM Lwin, CK Hsu… - … and Clinical Risk …, 2023 - Taylor & Francis
Dystrophic epidermolysis bullosa (DEB) is one of the major types of EB, a rare hereditary
group of trauma-induced blistering skin disorders. DEB is caused by inherited pathogenic …

Mesenchymal Stem Cell Aggregation‐Released Extracellular Vesicles Induce CD31+EMCN+ Vessels in Skin Regeneration and Improve Diabetic Wound Healing

L Liu, CX Zheng, N Zhao, T Zhu, CB Hu… - Advanced …, 2023 - Wiley Online Library
The blood vessel system is essential for skin homeostasis and regeneration. While the
heterogeneity of vascular endothelial cells has been emergingly revealed, whether a …

Mesenchymal Stem Cell Culture within Perfusion Bioreactors Incorporating 3D‐Printed Scaffolds Enables Improved Extracellular Vesicle Yield with Preserved …

SM Kronstadt, DB Patel, LJ Born, D Levy… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are implicated as promising therapeutics and drug delivery
vehicles in various diseases. However, successful clinical translation will depend on the …

Extracellular vesicles in fatty liver disease and steatohepatitis: Role as biomarkers and therapeutic targets

A Eguchi, M Iwasa, H Nakagawa - Liver International, 2023 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) and alcohol‐associated liver disease (ALD) are
characterized by lipid deposition in hepatocytes in the absence or presence of excessive …

[HTML][HTML] dCas9-Based PDGFR–β Activation ADSCs Accelerate Wound Healing in Diabetic Mice through Angiogenesis and ECM Remodeling

Y Li, D Li, L You, T Deng, Q Pang, X Meng… - International Journal of …, 2023 - mdpi.com
The chronic wound represents a serious disease characterized by a failure to heal damaged
skin and surrounding soft tissue. Mesenchymal stem cells (MSCs) derived from adipose …

Loading nanoceria improves extracellular vesicle membrane integrity and therapy to wounds in aged mice

L Gao, Q Feng, B Cui, Y Mao, Z Zhao… - … biomaterials science & …, 2023 - ACS Publications
Wound healing is a programmed process through which tissue restores its integrity after an
injury. Advancing age is a risk factor for delayed cutaneous wound healing; however, ideal …

Biodistribution-based Administration of cGMP-compliant Human Umbilical Cord Mesenchymal Stem Cells Affects the Therapeutic Effect of Wound Healing

X Wang, Q Wang, L Meng, R Tian, H Guo, Z Tan… - Stem Cell Reviews and …, 2024 - Springer
Background Although mesenchymal stem cells (MSCs) are used as therapeutic agents for
skin injury therapy, few studies have reported the effects of dosing duration and delivery …

Physiology and pathophysiology of wound healing in diabetes

I Pastar, NC Balukoff, AP Sawaya, NM Vecin… - The Diabetic Foot …, 2024 - Springer
Wound healing is a dynamic process comprising of overlapping phases of hemostasis,
inflammation, proliferation, and remodeling that involve multiple cell types. This highly …

Check for Physiology and Pathophysiology of Wound Healing in Diabetes Irena Pastar, Nathan C. Balukoff, Andrew P. Sawaya, Nicole M. Vecin and Marjana Tomic …

I Pastar - The Diabetic Foot: Medical and Surgical Management - books.google.com
Wound healing is a dynamic process comprising of overmany cellular responses including
inflammation, proliferation, migration, angiogenesis and tissue remodeling. lapping phases …