Sex differences in cardiovascular actions of the renin–angiotensin system

D Medina, D Mehay, AC Arnold - Clinical Autonomic Research, 2020 - Springer
Cardiovascular disease (CVD) remains a worldwide public health concern despite decades
of research and the availability of numerous targeted therapies. While the intrinsic …

Twenty years of studying AngII (angiotensin II)-induced abdominal aortic pathologies in mice: continuing questions and challenges to provide insight into the human …

H Sawada, HS Lu, LA Cassis… - … thrombosis, and vascular …, 2022 - Am Heart Assoc
AngII (angiotensin II) infusion in mice has been used to provide mechanistic insight into
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …

Potential mechanisms of cerebrovascular diseases in COVID-19 patients

M Lou, D Yuan, S Liao, L Tong, J Li - Journal of NeuroVirology, 2021 - Springer
Since the outbreak of coronavirus disease 2019 (COVID-19) in 2019, it is gaining worldwide
attention at the moment. Apart from respiratory manifestations, neurological dysfunction in …

[HTML][HTML] Angiotensin-(1-7)/MasR axis promotes migration of monocytes/macrophages with a regulatory phenotype to perform phagocytosis and efferocytosis

I Zaidan, LP Tavares, MA Sugimoto, KM Lima… - JCI insight, 2022 - ncbi.nlm.nih.gov
Nonphlogistic migration of macrophages contributes to the clearance of pathogens and
apoptotic cells, a critical step for the resolution of inflammation and return to homeostasis …

Angiotensin-(1-7): translational avenues in cardiovascular control

D Medina, AC Arnold - American journal of hypertension, 2019 - academic.oup.com
Despite decades of research and numerous treatment approaches, hypertension and
cardiovascular disease remain leading global public health problems. A major contributor to …

[HTML][HTML] Angiotensin-converting enzyme 2, coronavirus disease 2019, and abdominal aortic aneurysms

B Xu, G Li, J Guo, T Ikezoe, K Kasirajan, S Zhao… - Journal of Vascular …, 2021 - Elsevier
Objective Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the etiologic
agent of the current, world-wide coronavirus disease 2019 (COVID-19) pandemic …

Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice

L Zhang, H Zhang, J Ma, Y Wang… - International …, 2022 - spandidos-publications.com
Herbal medicines have attracted much attention in recent years and are increasingly being
used as alternatives to pharmaceutical medicines. Thymoquinone (TQ) is one of the most …

Mas receptor: a potential strategy in the management of ischemic cardiovascular diseases

A Molaei, E Molaei, AW Hayes, G Karimi - Cell Cycle, 2023 - Taylor & Francis
MasR is a critical element in the RAS accessory pathway that protects the heart against
myocardial infarction, ischemia-reperfusion injury, and pathological remodeling by …

Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin‐Deficient Mice via Upregulation of Angiotensin (1–7)

K Karasaki, H Kokubo, B Bumdelger… - Journal of the …, 2023 - Am Heart Assoc
Background Angiotensin II type 1 receptor blockers (ARBs) have been shown to limit the
growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial. This study …

Male bias in ACE2 basic science research: Missed opportunity for discovery in the time of COVID-19

B Miličić Stanić, S Maddox… - American Journal …, 2021 - journals.physiology.org
Throughout the world, including the United States, men have worse outcomes from COVID-
19 than women. SARS-CoV-2, the causative virus of the COVID-19 pandemic, uses …