Synergistic Effect of Flavonoids and Metformin on Protection of the Methylglyoxal-Induced Damage in PC-12 Neuroblastoma Cells: Structure–Activity Relationship and …

D Zhang, X He, T Wang, Y Xing, Z Xiu, Y Bao, Y Dong - Molecules, 2024 - mdpi.com
Methylglyoxal-induced ROS elevation is the primary cause of neuronal damage. Metformin
is a traditional hypoglycemic drug that has been reported to be beneficial to the nervous …