Inosine pranobex (IP), commonly known as inosine acedoben dimepranol, isoprinosine and
methisoprinol, has been proven to positively impact the host's immune system, by enhancing …

Tuberculosis is a highly contagious disease spread by Mycobacterium tuberculosis. It is
responsible for highest numbers of death and soon will surpass the deaths caused by HIV …

There is an urgent need for the discovery and development of new antitubercular agents that
target new biochemical pathways and treat drug resistant forms of the disease. One …

Structural modification of the frontline antitubercular isonicotinic acid hydrazide (INH)
provides lipophilic adaptations (3–46) of the drug in which the hydrazine moiety of the …

Tuberculosis (TB), caused by the bacterial organism Mycobacterium tuberculosis, pose a
major threat to public health, especially in middle and low-income countries. Worldwide in …

Tuberculosis (TB), derived from bacterium named Mycobacterium tuberculosis, has become
one of the worst infectious and contagious illnesses in the world after HIV/AIDS. Long-term …

Bedaquiline (1) is a new drug for tuberculosis and the first of the diarylquinoline class. It
demonstrates excellent efficacy against TB but induces phospholipidosis at high doses, has …

The use of laboratory animals is critical to the discovery and in vivo pre-clinical testing of
new drugs and drug combinations for use in humans. M. tuberculosis infection of mice, rats …

This article provides a critical review of the different applications of ferrocene‐based
peptides/amides in biological as well as in non‐biological systems. Ferrocene‐based …

A series of biphenyl analogues of the new tuberculosis drug PA-824 was prepared, primarily
by coupling the known (6 S)-2-nitro-6, 7-dihydro-5 H-imidazo [2, 1-b][1, 3] oxazin-6-ol with …