Coronary artery spasm-related heart failure syndrome: Literature review
MJ Hung, CT Yeh, NG Kounis, I Koniari, P Hu… - International journal of …, 2023 - mdpi.com
Although heart failure (HF) is a clinical syndrome that becomes worse over time, certain
cases can be reversed with appropriate treatments. While coronary artery spasm (CAS) is …
cases can be reversed with appropriate treatments. While coronary artery spasm (CAS) is …
Development of new genome editing tools for the treatment of hyperlipidemia
G Preta - Cells, 2023 - mdpi.com
Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is
often associated with an increased risk of cardiovascular diseases such as heart attacks and …
often associated with an increased risk of cardiovascular diseases such as heart attacks and …
[HTML][HTML] Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE-/-mice
P Xiang, Q Chen, L Chen, J Lei, Z Yuan, H Hu, Y Lu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Atherosclerosis (AS) is still the major cause of cardiovascular disease (CVD)
as well as stroke. Endothelial metabolic disorder has been found to be activated and then …
as well as stroke. Endothelial metabolic disorder has been found to be activated and then …
TREM2 protects from atherosclerosis by limiting necrotic core formation
M Piollet, F Porsch, G Rizzo, F Kapser… - Nature cardiovascular …, 2024 - nature.com
Atherosclerosis is a chronic disease of the vascular wall driven by lipid accumulation and
inflammation in the intimal layer of arteries, and its main complications—myocardial …
inflammation in the intimal layer of arteries, and its main complications—myocardial …
Differences in vasomotor function of mesenteric arteries between Ossabaw minipigs with predisposition to metabolic syndrome and Göttingen minipigs
C Eickelmann, HR Lieder, M Sturek… - American Journal …, 2024 - journals.physiology.org
Metabolic syndrome predisposes and contributes to the development and progression of
atherosclerosis. The minipig strain “Ossabaw” is characterized by a predisposition to …
atherosclerosis. The minipig strain “Ossabaw” is characterized by a predisposition to …
Tanshinone IIA alleviates atherosclerosis in LDLR−/− mice by regulating efferocytosis of macrophages
J Wang, Y Zhang, X Feng, M Du, S Li… - Frontiers in …, 2023 - frontiersin.org
Background: Tanshinone IIA (TIIA) is the major lipid-soluble active ingredient of the
traditional Chinese medicine Salvia miltiorrhiza, which slows down atherosclerosis (AS) …
traditional Chinese medicine Salvia miltiorrhiza, which slows down atherosclerosis (AS) …
[HTML][HTML] Gonadal sex vs genetic sex in experimental atherosclerosis
Epidemiological data and interventional studies with hormone replacement therapy suggest
that women, at least until menopause, are at decreased cardiovascular risk compared to …
that women, at least until menopause, are at decreased cardiovascular risk compared to …
The growing importance of basic models of cardiovascular disease
A Rosenzweig - Circulation research, 2022 - Am Heart Assoc
The past decade has witnessed an explosion in the tools, resources, and publicly available
data for human-based discovery implicating multiple new candidate pathways and potential …
data for human-based discovery implicating multiple new candidate pathways and potential …
[HTML][HTML] Apoe-knockout induces strong vascular oxidative stress and significant changes in the gene expression profile related to the pathways implicated in redox …
B Liu, L Fang, P Mo, C Chen, Y Ji, L Pang, H Chen… - Cellular …, 2023 - Elsevier
Apolipoprotein E (APOE) was recognized as a key regulator of lipid metabolism, which
prompted the Apoe-knockout (Apoe−/−) mouse to be the most widely used atherosclerotic …
prompted the Apoe-knockout (Apoe−/−) mouse to be the most widely used atherosclerotic …
Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse
Mouse models have been used extensively to study human coronary artery disease (CAD)
or atherosclerosis and to test therapeutic targets. However, whether mouse and human …
or atherosclerosis and to test therapeutic targets. However, whether mouse and human …