Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

Alzheimer's disease (AD) is the most common form of dementia worldwide, with a complex,
poorly understood pathogenesis. Cerebral atrophy, amyloid-β (Aβ) plaques, and …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain, which is
characterized by the formation of extracellular amyloid plaques (or senile plaques) and …

Alzheimer's disease (AD) is a biologically complex neurodegenerative dementia. Nearly 20
years ago, with the combination of observations from biochemistry, neuropathology and …

The endoplasmic reticulum (ER) is a dynamic intracellular organelle with multiple functions
essential for cellular homeostasis, development, and stress responsiveness. In response to …

A variety of stimuli utilize an increase of cytosolic free Ca2+ concentration as a second
messenger to transmit signals, through Ca2+ release from the endoplasmic reticulum or …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases, yet
current therapeutic treatments are inadequate due to a complex disease pathogenesis. The …

Introduction• Protein aggregation‐'Toxic oligomer'hypothesis‐Protein (mis) folding‐
Proteostasis and molecular chaperones‐Protein misfolding and endoplasmic reticulum …

Background Chronic hypertension, particularly midlife high blood pressure, has been
associated with an increased risk for cognitive decline and dementia. In this context …

Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …