Background Chimeric antigen receptor (CAR)‐T‐cell therapies have revolutionized the
management of acute lymphoblastic leukemia, non‐Hodgkin lymphoma, and multiple …

Spontaneous reporting systems remain pivotal for post-marketing surveillance and
disproportionality analysis (DA) represents a recognized approach for early signal detection …

Mepolizumab is primarily used in the treatment of asthma, eosinophilic granulomatosis with
polyangiitis, eosinophilia syndrome, and chronic rhinitis with nasal polyps. The information …

Introduction Impulse control disorders (eg pathological gambling, hypersexuality) may
develop as adverse reactions to drugs. Pathogenetic hypotheses have mainly focused on …

Background Drug toxicity does not affect patients equally; the toxicity may only exert in
patients who possess certain attributes of susceptibility to specific drug properties (ie, drug …

Simple Summary Targeted therapies in children with hematological malignancies moderate
the effects of cytotoxic therapy, thus improving survival rates. They have emerged over the …

In pharmacovigilance, disproportionality analyses based on individual case safety reports
are widely used to detect safety signals. Unfortunately, publishing disproportionality …

Chimeric antigen receptor (CAR) T-cell therapy has greatly transformed the treatment and
prognosis of B-cell hematological malignancies. As CAR T-cell therapy continues to be more …

CAR T-cells have revolutionized the treatment of many hematological malignancies.
Thousands of patients with lymphoma, acute lymphoblastic leukemia, and multiple myeloma …

Axicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) are chimeric antigen
receptor (CAR) T-cell therapies used to treat adult patients with relapsed or refractory …