[HTML][HTML] Pharmacological inhibitors of the NLRP3 inflammasome

A Zahid, B Li, AJK Kombe, T Jin, J Tao - Frontiers in immunology, 2019 - frontiersin.org
Inflammasomes play a crucial role in innate immunity by serving as signaling platforms
which deal with a plethora of pathogenic products and cellular products associated with …

[HTML][HTML] Sesquiterpenoids lactones: benefits to plants and people

M Chadwick, H Trewin, F Gawthrop… - International journal of …, 2013 - mdpi.com
Sesquiterpenoids, and specifically sesquiterpene lactones from Asteraceae, may play a
highly significant role in human health, both as part of a balanced diet and as …

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives

E Ozaki, M Campbell, SL Doyle - Journal of inflammation research, 2015 - Taylor & Francis
The inflammasome is a molecular platform formed by activation of an innate immune pattern
recognition receptor seed, such as NLRP3. Once activated, NLRP3 recruits the adapter ASC …

The biochemistry and medical significance of the flavonoids

BH Havsteen - Pharmacology & therapeutics, 2002 - Elsevier
Flavonoids are plant pigments that are synthesised from phenylalanine, generally display
marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are …

[HTML][HTML] Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome

C Juliana, T Fernandes-Alnemri, J Wu, P Datta… - Journal of Biological …, 2010 - ASBMB
Activation of the inflammasome generates the pro-inflammatory cytokines interleukin-1β and-
18, which are important mediators of inflammation. Abnormal activation of the inflammasome …

Medicinal halophytes: potent source of health promoting biomolecules with medical, nutraceutical and food applications

R Ksouri, WM Ksouri, I Jallali, A Debez… - Critical reviews in …, 2012 - Taylor & Francis
Salt-tolerant plants grow in a wide variety of saline habitats, from coastal regions, salt
marshes and mudflats to inland deserts, salt flats and steppes. Halophytes living in these …

Targeting apoptosis pathways in cancer and perspectives with natural compounds from mother nature

FM Millimouno, J Dong, L Yang, J Li, X Li - Cancer prevention research, 2014 - AACR
Although the incidences are increasing day after day, scientists and researchers taken
individually or by research group are trying to fight against cancer by several ways and also …

Recent developments in anti‐inflammatory natural products

R Gautam, SM Jachak - Medicinal research reviews, 2009 - Wiley Online Library
Many of the inflammatory diseases are becoming common in aging society throughout the
world. The clinically used anti‐inflammatory drugs suffer from the disadvantage of side …

Antibacterial activities of medicinal plants used in Mexican traditional medicine

A Sharma, R del Carmen Flores-Vallejo… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance We provide an extensive summary of the in vitro
antibacterial properties of medicinal plants popularly used in Mexico to treat infections, and …

Ethnobotany and its role in drug development

M Heinrich - … Research: An International Journal Devoted to …, 2000 - Wiley Online Library
The botanical collections of early explorers and the later ethnobotany have played important
roles in the development of new drugs for many centuries. In the middle of the last century …