Identification of NLRP3PYD Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity
S Moasses Ghafary, PM Soriano-Teruel… - International Journal of …, 2022 - mdpi.com
Inflammasomes are multiprotein complexes that represent critical elements of the
inflammatory response. The dysregulation of the best-characterized complex, the NLRP3 …
inflammatory response. The dysregulation of the best-characterized complex, the NLRP3 …
First discovery of cholesterol-lowering activity of parthenolide as NPC1L1 inhibitor
W Liu, B Liang, J Zeng, J Meng, L Shi, S Yang, J Chang… - Molecules, 2022 - mdpi.com
Elevated cholesterol significantly increases the risk of developing atherosclerosis and
coronary heart disease. The key to treating hypercholesterolemia is lowering plasma …
coronary heart disease. The key to treating hypercholesterolemia is lowering plasma …
Lactones: generic inhibitors of enzymes?
MI Konaklieva, BJ Plotkin - Mini reviews in medicinal chemistry, 2005 - ingentaconnect.com
The ability to affect eukaryotic and prokaryotic cellular growth, signaling and differentiation is
a continuing focus in the pharmaceutical industry. The fundamental ability to affect these …
a continuing focus in the pharmaceutical industry. The fundamental ability to affect these …
Parthenolide is neuroprotective in rat experimental stroke model: downregulating NF‐κB, phospho‐p38MAPK, and caspase‐1 and ameliorating BBB permeability
L Dong, H Qiao, X Zhang, X Zhang… - Mediators of …, 2013 - Wiley Online Library
Inflammatory damage plays an important role in cerebral ischemic pathogenesis and may
represent a target for treatment. Parthenolide (PN) has been proved to elicit a wide range of …
represent a target for treatment. Parthenolide (PN) has been proved to elicit a wide range of …
Zapotec and Mixe use of tropical habitats for securing medicinal plants in Mexico
B Frei, O Sticher, M Heinrich - Economic Botany, 2000 - JSTOR
Medicinal plants are essential in the medical systems of the Mixe and Zapotec. In this study
ethno-ecological strategies, employed by the two neighboring Indian groups in Mexico, for …
ethno-ecological strategies, employed by the two neighboring Indian groups in Mexico, for …
Outstanding anti-inflammatory potential of selected Asteraceae species through the potent dual inhibition of cyclooxygenase-1 and 5-lipoxygenase
DA Chagas-Paula, TB Oliveira, DPV Faleiro… - Planta …, 2015 - thieme-connect.com
Cyclooxygenase and 5-lipoxygenase are enzymes that catalyze important inflammatory
pathways, suggesting that dual cyclooxygenase/lipoxygenase inhibitors should be more …
pathways, suggesting that dual cyclooxygenase/lipoxygenase inhibitors should be more …
North American Artemisia species from the subgenus Tridentatae (Sagebrush): A phytochemical, botanical and pharmacological review
The genus Artemisia consists of between 350 and 500 species with most of the North
American endemic Artemisia species contained within the subgenus Tridentatae …
American endemic Artemisia species contained within the subgenus Tridentatae …
[PDF][PDF] Actualidad de la medicina tradicional herbolaria
S Prieto-González, G Garrido-Garrido… - Revista CENIC …, 2004 - redalyc.org
La Medicina Tradicional ha desempeñado un papel importante en el tratamiento de
diversas patologías, fundamentalmente en los países en desarrollo. En ellos, el 80% de la …
diversas patologías, fundamentalmente en los países en desarrollo. En ellos, el 80% de la …
Knowledge and demand for medicinal plants used in the treatment and management of diabetes in Nyeri County, Kenya
Ethnopharmacological relevance Non communicable diseases are currently a major health
challenge facing humanity. Nyeri County has one of the highest diabetes prevalence in …
challenge facing humanity. Nyeri County has one of the highest diabetes prevalence in …
Traditional medicinal plants in South Tyrol (northern Italy, southern Alps): Biodiversity and use
J Petelka, B Plagg, I Säumel, S Zerbe - Journal of Ethnobiology and …, 2020 - Springer
Background Worldwide mountain regions are recognized as hotspots of
ethnopharmacologically relevant species diversity. In South Tyrol (Southern Alps, Italy), and …
ethnopharmacologically relevant species diversity. In South Tyrol (Southern Alps, Italy), and …