Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …

Microtubule affinity‐regulating kinase 4 (MARK4) is a member of the Ser/Thr protein kinase
family, phosphorylates the microtubule‐connected proteins and plays a vital role in causing …

There are some reported anticancer and antibacterial effects for embelin, although, it's poor
aqueous solubility and bioavailability are main hindrance to apply embelin in therapeutics …

Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study,
bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α …

Microtubule affinity regulating kinase 4 (MARK4) is known to hyperphosphorylate tau
protein, which subsequently causes Alzheimer's disease (AD). MARK4 is a well-validated …

Rho-associated protein kinase 1 (ROCK1) is a member of the AGC family which plays
crucial roles in inflammatory diseases and cancer progression. Elevated expression of …

PIM-1 kinase is a member of the Ser/Thr kinases family, a well-studied therapeutic target for
cancer therapy. The overexpression of PIM-1 is associated with prostate and breast cancer …

Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase that plays an essential role in
signal transduction across different cell types. In the context of allergy and autoimmune …

Abstract Phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA)
plays a crucial role in signaling pathways and has emerged as an attractive target for …

Protein S-palmitoylation mediated by DHHCs is recognized as a distinct and reversible form
of lipid modification connected with several health perturbations, including …