Neuropathy will afflict over half of the estimated 460 million people worldwide who have
diabetes, 303 of whom approximately onethird will also develop neuropathic pain. 2 The …

Abstract Treatment of neuropathic pain remains inadequate despite the elucidation of
multiple pathophysiological mechanisms and the development of promising therapeutic …

Large variability in the individual response to even the most-efficacious pain treatments is
observed clinically, which has led to calls for a more personalized, tailored approach to …

For patients diagnosed with a rare musculoskeletal or neuromuscular disease, pain may
transition from acute to chronic; the latter yielding additional challenges for both patients and …

The management of chronic neuropathic pain remains a challenge, because pain is
subjective, and measuring it objectively is usually out of question. However, neuropathic …

Managing chronic pain remains a major unmet clinical challenge. Patients can be treated
with a range of interventions, but pharmacotherapy is the most common. These include …

Chronic pain is a constantly recurring and persistent illness, presenting a formidable
healthcare challenge for patients and physicians alike. Current first‐line analgesics offer …

Background Neuropathic pain is common and difficult to treat. The sodium channel blocker
lacosamide is efficacious in animal models of pain, but its effect on neuropathic pain in …

Neuropathic pain is a chronic and debilitating condition characterised by episodes of
hyperalgesia and allodynia. It occurs following nerve damage from disease, inflammation or …

Orofacial pain (OFP) is a dental specialty that includes the diagnosis, management and
treatment of disorders of the jaw, mouth, face, head and neck. Evidence-based …