[HTML][HTML] Molecular mechanisms of ferroptosis and their involvement in brain diseases

I Costa, DJ Barbosa, S Benfeito, V Silva… - Pharmacology & …, 2023 - Elsevier
Ferroptosis is a type of regulated cell death characterized by intracellular accumulation of
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …

A systematic review of the incidence, prevalence, costs, and activity and work limitations of amputation, osteoarthritis, rheumatoid arthritis, back pain, multiple sclerosis …

J Lo, L Chan, S Flynn - Archives of physical medicine and rehabilitation, 2021 - Elsevier
Objectives To present recent evidence on the prevalence, incidence, costs, activity
limitations, and work limitations of common conditions requiring rehabilitation. Data Sources …

The prevalence of MS in the United States: a population-based estimate using health claims data

MT Wallin, WJ Culpepper, JD Campbell, LM Nelson… - Neurology, 2019 - AAN Enterprises
Objective To generate a national multiple sclerosis (MS) prevalence estimate for the United
States by applying a validated algorithm to multiple administrative health claims (AHC) …

Epidemiology and treatment of multiple sclerosis in elderly populations

CB Vaughn, D Jakimovski, KS Kavak… - Nature Reviews …, 2019 - nature.com
The prevalence of multiple sclerosis (MS) and the age of affected patients are increasing
owing to increased longevity of the general population and the availability of effective …

Current and future biomarkers in multiple sclerosis

J Yang, M Hamade, Q Wu, Q Wang, R Axtell… - International journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is a debilitating autoimmune disorder. Currently, there is a lack of
effective treatment for the progressive form of MS, partly due to insensitive readout for …

The genetics of multiple sclerosis: from 0 to 200 in 50 years

SE Baranzini, JR Oksenberg - Trends in genetics, 2017 - cell.com
Multiple sclerosis (MS) is a common autoimmune disease that targets myelin in the central
nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 …

Disease modifying therapies for relapsing multiple sclerosis

DM Wingerchuk, BG Weinshenker - Bmj, 2016 - bmj.com
Multiple sclerosis (MS) is a common, disabling, putatively autoimmune neurological disease
with worldwide distribution. It typically begins as a relapsing disorder that later evolves to a …

The safety and efficacy of low‐dose naltrexone in the management of chronic pain and inflammation in multiple sclerosis, fibromyalgia, Crohn's disease, and other …

DK Patten, BG Schultz, DJ Berlau - … : The Journal of Human …, 2018 - Wiley Online Library
Chronic inflammatory diseases are complex to treat and have an impact on a large number
of patients. Due to the difficulty of treating these diseases and the great impact on quality of …

Gut microbiota in multiple sclerosis and experimental autoimmune encephalomyelitis: current applications and future perspectives

F Chu, M Shi, Y Lang, D Shen, T Jin… - Mediators of …, 2018 - Wiley Online Library
The gut environment and gut microbiome dysbiosis have been demonstrated to significantly
influence a range of disorders in humans, including obesity, diabetes, rheumatoid arthritis …

[HTML][HTML] Estimating prevalence, demographics, and costs of ME/CFS using large scale medical claims data and machine learning

AR Valdez, EE Hancock, S Adebayo… - Frontiers in …, 2019 - frontiersin.org
Techniques of data mining and machine learning were applied to a large database of
medical and facility claims from commercially insured patients to determine the prevalence …