Angiocentric CD3+ T-Cell Infiltrates in Human Immunodeficiency Virus Type 1-Associated Central Nervous System Disease in Children

CD Katsetos, JE Fincke, A Legido… - Clinical Diagnostic …, 1999 - Am Soc Microbiol
ABSTRACT A significant proportion of brain tissue specimens from children with AIDS show
evidence of vascular inflammation in the form of transmural and/or perivascular …

Effects of HIV-1 Vpr on neuroinvasion and neuropathogenesis

RJ Pomerantz - DNA and cell biology, 2004 - liebertpub.com
Human immunodeficiency virus type I (HIV-1) infection leads to penetration of the central
nervous system (CNS) in virtually all infected individuals and HIV-1–induced …

Isolation and long-term culture of primary ocular human immunodeficiency virus type 1 isolates in primary astrocytes

M Canki, MJ Potash, G Bentsman, W Chao… - Journal of …, 1997 - Taylor & Francis
Vitreous specimens from 14 HIV-1 infected persons undergoing medically indicated
vitrectomy were assayed for the presence of infectious HIV-1 and viral tropism. Human …

Human Immunodeficiency Virus-1 (HIV-1)-Tat Protein Promotes Migration of Acquired Immunodeficiency Syndrome–Related Lymphoma Cells and Enhances Their …

RGS Chirivi, G Taraboletti, MR Bani… - Blood, The Journal …, 1999 - ashpublications.org
Abstract Human immunodeficiency virus-1 (HIV-1)-Tat, the transactivating gene product of
HIV-1, has been shown to interact with different cell types, inducing gene expression …

Establishment of an HIV cell–cell fusion assay by using two genetically modified HeLa cell lines and reporter gene

T Sakamoto, H Ushijima, S Okitsu, E Suzuki… - Journal of virological …, 2003 - Elsevier
Infection of human cells with the human immunodeficiency virus type I (HIV-1) can be
mimicked by a fusion process between cells expressing the HIV envelope protein (Env) and …

Efficient infection of brain microvascular endothelial cells by an in vivo-selected neuroinvasive SIVmac variant

LI Strelow, DD Watry, HS Fox, JA Nelson - Journal of neurovirology, 1998 - Taylor & Francis
A neuroinvasive/neuropathogenic SIV variant termed SIVmac182 was previously isolated
and characterized (Watry et al, 1994). This neuroinvasive strain was derived from the …

Neuroimmune and neurovirological aspects of human immunodeficiency virus infection

C Power, RT Johnson - Advances in virus research, 2001 - Elsevier
Like most lentiviruses, HIV-1 causes both immune suppression and neurological disease.
Neurological disease may occur at any stage of HIV infection but is most apparent with …

The blood-brain barrier and AIDS

LI Strelow, D Janigro, JA Nelson - Advances in virus research, 2001 - Elsevier
Publisher Summary This chapter focuses on how human immunodeficiency virus (HIV) and
simian immunodeficiency virus (SIV) are proposed to interact with and cross the blood–brain …

Kunjin replicon-based simian immunodeficiency virus gag vaccines

I Anraku, VV Mokhonov, P Rattanasena, EI Mokhonova… - Vaccine, 2008 - Elsevier
An RNA-based, non-cytopathic replicon vector system, based on the flavivirus Kunjin, has
shown considerable promise as a new vaccine delivery system. Here we describe the …

Reliable Estimation of CD8 T Cell Inhibition of In Vitro HIV-1 Replication

Y Xu, AM Weideman, M Abad-Fernandez… - Frontiers in …, 2021 - frontiersin.org
The HIV-1 viral inhibition assay (VIA) measures CD8 T cell-mediated inhibition of HIV
replication in CD4 T cells and is increasingly used for clinical testing of HIV vaccines and …