Escape from senescence: molecular basis and therapeutic ramifications

K Evangelou, K Belogiannis… - The Journal of …, 2023 - Wiley Online Library
Cellular senescence constitutes a stress response mechanism in reaction to a plethora of
stimuli. Senescent cells exhibit cell‐cycle arrest and altered function. While cell‐cycle …

Neutrophil extracellular traps and long COVID

A Shafqat, MH Omer, I Albalkhi… - Frontiers in …, 2023 - frontiersin.org
Post-acute COVID-19 sequelae, commonly known as long COVID, encompasses a range of
systemic symptoms experienced by a significant number of COVID-19 survivors. The …

A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells

S Magkouta, D Veroutis, A Pousias… - Molecular Cell, 2023 - cell.com
Cellular senescence is a stress-response mechanism implicated in various physiological
processes, diseases, and aging. Current detection approaches have partially addressed the …

Examining the wound healing potential of curcumin-infused electrospun nanofibers from polyglutamic acid and gum arabic

C Cheng, R Wang, J Ma, Y Zhang, Q Jing… - International Journal of …, 2024 - Elsevier
Advancements in medicine have led to continuous enhancements and innovations in wound
dressing materials, making them pivotal in medical care. We used natural biological …

A unified model of age-related cardiovascular disease

M Fossel, J Bean, N Khera, MG Kolonin - Biology, 2022 - mdpi.com
Simple Summary Age-related cardiovascular disease is the foremost cause of death
globally. Despite medical advances, we have been unable to stop or reverse the underlying …

Epigenetic regulations of cellular senescence in osteoporosis

S Huo, X Tang, W Chen, D Gan, H Guo, Q Yao… - Ageing Research …, 2024 - Elsevier
Osteoporosis (OP) is a prevalent age-related disease that is characterized by a decrease in
bone mineral density (BMD) and systemic bone microarchitectural disorders. With age …

Identification and functional analysis of senescent cells in the cardiovascular system using omics approaches

SA Mahoney, AK Dey, N Basisty… - American Journal of …, 2023 - journals.physiology.org
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and
senescent cells have emerged as key contributors to its pathogenesis. Senescent cells …

Arterial Stiffness: From Basic Primers to Integrative Physiology

V Regnault, P Lacolley, S Laurent - Annual Review of …, 2024 - annualreviews.org
The elastic properties of conductance arteries are one of the most important hemodynamic
functions in the body, and data continue to emerge regarding the importance of their …

A biomarker framework for cardiac aging: the Aging Biomarker Consortium consensus statement

Aging Biomarker Consortium, W Zhang, Y Che… - Life …, 2023 - academic.oup.com
Cardiac aging constitutes a significant risk factor for cardiovascular diseases prevalent
among the elderly population. Urgent attention is required to prioritize preventive and …

Activatable photoacoustic bioprobe for visual detection of aging in vivo

Z Li, J Cheng, P Huang, G Wu, W Lin - Chinese Chemical Letters, 2024 - Elsevier
Aging is a natural physiological process with various challenges, related to the loss of
homeostasis within the organism, which is not a disease, but a significantly strong risk factor …