Hypomagnesemia is commonly observed in heart failure, diabetes mellitus, hypertension,
and cardiovascular diseases. Low serum magnesium (Mg) is a predictor for cardiovascular …

Cardiac arrhythmias can cause sudden cardiac death (SCD) and add to the current heart
failure (HF) health crisis. Nevertheless, the pathological processes underlying arrhythmias …

Alterations in the antioxidant cellular system have often been proposed as biomarkers of
pollutant-mediated toxicity. This study evaluated the effects of mercury on oxidative stress …

The complex physiological signal transduction networks that respond to the dual challenges
of inflammatory and oxidative stress are major factors that promote the development of …

Significance: Over-nutrition and sedentary lifestyle has led to a worldwide increase in
obesity, insulin resistance, and type 2 diabetes (T2D) associated with an increased risk of …

Rationale: Pyridine nucleotides regulate the cardiac Na+ current (I Na) through generation
of reactive oxygen species (ROS). Objective: We investigated the source of ROS induced by …

Background: Atrial fibrillation (AF) has been associated with myocardial oxidative stress, and
antioxidant agents have demonstrated antiarrhythmic benefit in humans. We compared …

Mitochondria are essential to providing ATP, thereby satisfying the energy demand of the
incessant electrical activity and contractile action of cardiac muscle. Emerging evidence …

It is now well known that oxidative stress promotes lipid peroxidation, protein oxidation,
activation of proteases, fragmentation of DNA and alteration in gene expression for …

Described as the 'single largest unmet need in cardiovascular medicine', heart failure with
preserved ejection fraction (HFpEF) remains an untreatable disease currently representing …