[HTML][HTML] Seeing is believing: Exploiting advances in structural biology to understand and engineer plant immunity
MA Outram, M Figueroa, J Sperschneider… - Current Opinion in Plant …, 2022 - Elsevier
Filamentous plant pathogens cause disease in numerous economically important crops.
These pathogens secrete virulence proteins, termed effectors, that modulate host cellular …
These pathogens secrete virulence proteins, termed effectors, that modulate host cellular …
Advancement in the breeding, biotechnological and genomic tools towards development of durable genetic resistance against the rice blast disease
Rice production needs to be sustained in the coming decades, as the changeable climatic
conditions are becoming more conducive to disease outbreaks. The majority of rice …
conditions are becoming more conducive to disease outbreaks. The majority of rice …
A designer rice NLR immune receptor confers resistance to the rice blast fungus carrying noncorresponding avirulence effectors
Y Liu, X Zhang, G Yuan, D Wang… - Proceedings of the …, 2021 - National Acad Sciences
Plant nucleotide-binding and leucine-rich repeat (NLR) receptors recognize avirulence
effectors directly through their integrated domains (IDs) or indirectly via the effector-targeted …
effectors directly through their integrated domains (IDs) or indirectly via the effector-targeted …
Computational Structural Genomics Unravels Common Folds and Novel Families in the Secretome of Fungal Phytopathogen Magnaporthe oryzae
K Seong, KV Krasileva - Molecular Plant-Microbe Interactions, 2021 - Am Phytopath Society
Structural biology has the potential to illuminate the evolution of pathogen effectors and their
commonalities that cannot be readily detected at the primary sequence level. Recent …
commonalities that cannot be readily detected at the primary sequence level. Recent …
Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors
Y Cao, F Kümmel, E Logemann… - Proceedings of the …, 2023 - National Acad Sciences
In plants, host–pathogen coevolution often manifests in reciprocal, adaptive genetic
changes through variations in host nucleotide-binding leucine-rich repeat immune receptors …
changes through variations in host nucleotide-binding leucine-rich repeat immune receptors …
A blast fungus zinc-finger fold effector binds to a hydrophobic pocket in host Exo70 proteins to modulate immune recognition in rice
JC De la Concepcion, K Fujisaki… - Proceedings of the …, 2022 - National Acad Sciences
Exocytosis plays an important role in plant–microbe interactions, in both pathogenesis and
symbiosis. Exo70 proteins are integral components of the exocyst, an octameric complex …
symbiosis. Exo70 proteins are integral components of the exocyst, an octameric complex …
Show me your ID: NLR immune receptors with integrated domains in plants
C Marchal, VA Michalopoulou, Z Zou… - Essays in …, 2022 - portlandpress.com
Nucleotide-binding and leucine-rich repeat receptors (NLRs) are intracellular plant immune
receptors that recognize pathogen effectors secreted into the plant cell. Canonical NLRs …
receptors that recognize pathogen effectors secreted into the plant cell. Canonical NLRs …
Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector
R Zdrzałek, Y Xi, T Langner, AR Bentham… - Proceedings of the …, 2024 - pnas.org
Bioengineering of plant immune receptors has emerged as a key strategy for generating
novel disease resistance traits to counteract the expanding threat of plant pathogens to …
novel disease resistance traits to counteract the expanding threat of plant pathogens to …
The E3 ubiquitin ligase OsRGLG5 targeted by the Magnaporthe oryzae effector AvrPi9 confers basal resistance against rice blast
Z Liu, J Qiu, Z Shen, C Wang, N Jiang, H Shi… - Plant Communications, 2023 - cell.com
Rice blast, caused by Magnaporthe oryzae, is one of the most devastating diseases of rice.
During infection, M. oryzae secretes effectors to facilitate blast development. Among these …
During infection, M. oryzae secretes effectors to facilitate blast development. Among these …
A single amino acid polymorphism in a conserved effector of the multihost blast fungus pathogen expands host-target binding spectrum
Accelerated gene evolution is a hallmark of pathogen adaptation and specialization
following host-jumps. However, the molecular processes associated with adaptive evolution …
following host-jumps. However, the molecular processes associated with adaptive evolution …