[HTML][HTML] From workout to molecular switches: How does skeletal muscle produce, sense, and transduce subcellular redox signals?

C Henriquez-Olguin, R Meneses-Valdes… - Free Radical Biology …, 2023 - Elsevier
Skeletal muscle is crucial for maintaining human health and overall quality of life. Acute
exercise introduces a multifaceted intracellular stress, with numerous post-translational …

Spaceflight on the ISS changed the skeletal muscle proteome of two astronauts

M Murgia, J Rittweger, C Reggiani, R Bottinelli… - npj …, 2024 - nature.com
Skeletal muscle undergoes atrophy and loss of force during long space missions, when
astronauts are persistently exposed to altered gravity and increased ionizing radiation. We …

Different Mechanisms in Doxorubicin-Induced Cardiomyopathy: Impact of BRCA1 and BRCA2 Mutations

HC Nguyen, JC Frisbee, KK Singh - Hearts, 2024 - mdpi.com
Germline mutations in Breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2)
cause breast, ovarian, and other cancers, and the chemotherapeutic drug doxorubicin (Dox) …

The Rho GTPase Rac1 mediates exercise training adaptations

SH Raun, C Henriquez-Olguin, E Frank, JR Knudsen… - bioRxiv, 2023 - biorxiv.org
Exercise training elicits tremendous health benefits; however, the molecular underpinnings
are poorly understood. As one of the most regulated groups of proteins following acute …