Lung neuroendocrine neoplasms (NENs) are a heterogeneous group of pulmonary
neoplasms showing different morphological patterns and clinical and biological …

Lung neuroendocrine neoplasms (NENs) encompass a spectrum of neoplasms that are
subdivided into the well-differentiated neuroendocrine tumors comprising the low-and …

Studies have shown that Nrf2 E79Q/+ is one of the most common mutations found in human
tumors. To elucidate how this genetic change contributes to lung cancer, we compared lung …

Background Organoids are 3-dimensional experimental models that summarize the
anatomical and functional structure of an organ. Although a promising experimental model …

MLL3 histone methyltransferase, encoded by the KMT2C gene, is a tumor suppressor that
has an essential role in cell‐type‐specific gene expression. We evaluated the prognostic …

Little is known as to whether there may be any pathogenetic link between pulmonary
carcinoids and neuroendocrine carcinomas (NECs). A gene signature we previously found …

Simple Summary Bronchial carcinoids (BCs) are uncommon and usually slow growing
neuroendocrine epithelial malignancies that represent less than 2% of all lung cancers …

Background Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with limited
treatment possibilities. Merkel cell tumors display with neuroendocrine features and Merkel …

Neuroendocrine neoplasms (NENs) of the cervix are rare aggressive tumors associated with
poor prognosis and only limited treatment options. Although there is some literature on …

Purpose: The primary origin of neuroendocrine tumor metastases can be difficult to
determine by histopathology alone, but is critical for therapeutic decision making. DNA …