High anesthetic exposure leads to oxidative damage and gene expression changes in physicians during medical residency: a cohort study

AG Aun, DC Damasceno, YK Sinzato… - … Science and Pollution …, 2023 - Springer
Abstract Evaluation of the possible toxic effects of occupational exposure to anesthetics is of
great importance, and the literature is limited in assessing the possible association between …

Environmentally Relevant Concentrations of Propofol-Induced Metabolic Dysfunction in Zebrafish: Mechanistic Insights into Integrated Hepatic Transcriptomic and …

N Jiang, X Li, G Zhang, Z Hu, X Fan, M Li, H Sun… - ACS ES&T …, 2024 - ACS Publications
Propofol is increasingly perceived as an emerging threat to aquatic ecosystems, although
the ecotoxicity and underlying mechanisms of propofol on aquatic life have not yet been …

Waste anesthetic gases have a significant association with deoxyribonucleic acid (DNA) damage: A systematic review and meta-analysis of 2,732 participants

MI Lestari, K Murti, IA Liberty, Z Hafy, V Linardi… - Heliyon, 2023 - cell.com
Introduction Operating room workers are at risk of experiencing adverse effects due to
occupational exposure to waste anesthetic gases (WAGs). One of the consequences of long …

Modulation of gene expression and influence of gene polymorphisms related to genotoxicity and redox status on occupational exposure to inhaled anesthetics

MAP Silva, DBS Figueiredo, LR de Carvalho… - International Journal of …, 2024 - Elsevier
Operating room professionals are constantly exposed to waste anesthetic gases (WAGs)
due to the extensive use of inhalational anesthetics (NIOSH-National Institute for …

Comparison between inhalational anesthetics in terms of DNA damage and immunological markers

MG Braz, MAP Silva, CE Scorza… - Environmental and …, 2024 - Wiley Online Library
This study compared genetic damage and immunological markers between surgical patients
who underwent inhalational anesthesia with isoflurane or sevoflurane. Blood samples were …

Veterinarians exposed to inhaled anesthetic present chromosome damage, apoptosis and cell cycle changes

MG Braz, DBS Figueiredo, MA Golim… - Environmental and …, 2024 - Wiley Online Library
This cross‐sectional study evaluated, for the first time, DNA damage, viability, and cell death
of lymphocytes and cell cycle phases of mononuclear and polymorphonuclear cells in …