Background Marijuana use among adolescents, including high school students, has been
consistently reported to be associated with a high incidence of suicidal behaviours. Little …

Objectives Despite increasing rates of legalization of medical cannabis worldwide, the
current evidence available on its effect on mental health outcomes including anxiety is of …

Background Cannabis use and nonmedical use of prescription opioids are consumed by a
small to moderate number of adolescents. However, little is known about their combined …

This study tested whether increases in recent and cumulative cannabis use were each
associated with increases in internalizing problems from adolescence to young adulthood …

Response variability across the lifespan is an important consideration in toxicology and risk
assessment, and the toxic effects of drugs and chemicals during adolescence need more …

Sex differences in both the endocannabinoid system and stress responses have been
established for decades. While there is ample evidence that the sexes respond differently to …

Objective: This study examined joint trends over time in associations between substance
use (heavy drinking, cannabis, and cigarette smoking) and mental health concerns …

Background: With the recent legalization of nonmedical cannabis in Canada, it is important
to document previous associations between cannabis use and major depressive episode …

Gender differences in psychiatric disorders and drug use are well known. Cannabis is the
most widely used illegal drug among young people. In recent years, its use has been related …

Background Legal access to medical cannabis is increasing world-wide. Despite this, there
is a lack of evidence surrounding its efficacy on mental health outcomes, particularly, on …