Multiple myeloma (MM) is the second common hematologic malignancy manifesting as a
clonal proliferation of plasma cells in the bone marrow. In recent years, high expression and …

Cephalotaxus is the only genus of Cephalotaxaceae family, and its natural resources are
declining due to habitat fragmentation, excessive exploitation and destruction. In many …

Acute myeloid leukemia (AML) is the most common type of leukemia in adults. AML cells
secrete angiogenic factors to remodel vasculature and acquire chemoresistance; however …

Background Bone marrow stromal cells (BMSCs) are known to promote chemoresistance in
acute myeloid leukemia (AML) cells. However, the molecular basis for BMSC-associated …

Adipogenesis of bone marrow mesenchymal stem cells (MSCs) promotes chemoresistance
of acute myeloid leukaemia (AML) cells. MSCs from AML patients (AML‐MSCs) display …

Acute myeloid leukemia (AML) cell survival and chemoresistance are influenced by the
existence of bone marrow mesenchymal stem cells (BMMSCs); however, the pathways by …

Homoharringtonine (HHT), a natural alkaloid derived from the cephalotaxus, exhibited its
anti-cancer effects in hematological malignancies clinically. However, its pesticide effects …

Homoharringtonine (HHT), an Food and Drug Administration (FDA)-approved anti-leukemia
drug, exerts anti-tumor activity in several solid tumors, including colorectal cancer (CRC) …

Tyrosine kinase inhibitors (TKIs) bring significant benefits for patients with cancers harboring
epidermal growth factor receptor (EGFR) mutations. However, after treatment for a certain …

Multiple myeloma (MM) accounts for~ 10% of all haematologic malignancies. Little is known
about high intratumour heterogeneities in patients stratified by the Revised International …