High-resolution tomographic analysis of in vitro 3D glioblastoma tumor model under long-term drug treatment

MS Ozturk, VK Lee, H Zou, RH Friedel, X Intes… - Science advances, 2020 - science.org
Glioblastoma multiforme (GBM) is a lethal type of brain tumor that often develop therapeutic
resistance over months of chemotherapy cycles. Recently, 3D GBM models were developed …

[HTML][HTML] Recent methodology advances in fluorescence molecular tomography

Y An, K Wang, J Tian - Visual Computing for Industry, Biomedicine, and Art, 2018 - Springer
Molecular imaging (MI) is a novel imaging discipline that has been continuously developed
in recent years. It combines biochemistry, multimodal imaging, biomathematics …

[HTML][HTML] Intravital mesoscopic fluorescence molecular tomography allows non-invasive in vivo monitoring and quantification of breast cancer growth dynamics

MS Ozturk, MG Montero, L Wang, LM Chaible… - Communications …, 2021 - nature.com
Preclinical breast tumor models are an invaluable tool to systematically study tumor
progression and treatment response, yet methods to non-invasively monitor the involved …

Accelerating vasculature imaging in tumor using mesoscopic fluorescence molecular tomography via a hybrid reconstruction strategy

F Yang, X Gong, D Faulkner, S Gao, R Yao… - Biochemical and …, 2021 - Elsevier
Mesoscopic fluorescent molecular tomography (MFMT) enables to image fluorescent
molecular probes beyond the typical depth limits of microscopic imaging and with enhanced …

Comparison of time-and angular-domain scatter rejection in mesoscopic optical projection tomography: a simulation study

L Sinha, F Massanes, VC Torres, C Li… - Biomedical Optics …, 2019 - opg.optica.org
Optical imaging offers exquisite sensitivity and resolution for assessing biological tissue in
microscopy applications; however, for samples that are greater than a few hundred microns …

Improving mesoscopic fluorescence molecular tomography via preconditioning and regularization

F Yang, R Yao, MS Ozturk, D Faulkner… - Biomedical Optics …, 2018 - opg.optica.org
Mesoscopic fluorescence molecular tomography (MFMT) is a novel imaging technique
capable of obtaining 3-D distribution of molecular probes inside biological tissues at depths …

System configuration optimization for mesoscopic fluorescence molecular tomography

F Yang, D Faulkner, R Yao, MS Ozturk… - Biomedical Optics …, 2019 - opg.optica.org
Tissue engineering applications demand 3D, non-invasive, and longitudinal assessment of
bioprinted constructs. Current emphasis is on developing tissue constructs mimicking in vivo …

Improving the performance of rapid lifetime determination for wide-field time-gated imaging in live cells

M Al-Salihi, Z Chen, S Samanta, A Elazab, R Yi… - Optics …, 2022 - opg.optica.org
In biological research, rapid wide-field fluorescence lifetime imaging has become an
important imaging tool. However, the biological samples with weak fluorescence signals and …

In-vivo monitoring and quantification of breast cancer growth dynamics with non-invasive intravital mesoscopic fluorescence molecular tomography

MS Ozturk, MG Montero, L Wang, LM Chaible… - bioRxiv, 2020 - biorxiv.org
Preclinical breast tumor models are an invaluable tool to systematically study tumor
progression and treatment response, yet methods to non-invasively monitor the involved …

Parallel Fast 3D Reconstruction for Tumor Microvascular Network in Mesoscopic Fluorescent Molecular Tomography

Y Chen, D Faulkner, F Yang - Clinical and Translational …, 2020 - opg.optica.org
To image the tumor microvascular network via mesoscopic fluorescent molecular
tomography, a fast-parallel 3D reconstruction method is presented. Experiments show the …