目的: 探讨III 期乳腺癌患者治疗前系统性炎症反应指数(SII), 中性粒细胞–淋巴细胞比值(NLR),
血小板–淋巴细胞比值(PLR) 和单核细胞–淋巴细胞比值(MLR) 与预后的相关性. 方法: 纳入2013 …

Abstract Akt/mTOR/p70S6K1 signaling pathway plays an important role in the pathogenesis
of cancer and diabetes. Macrophages and lymphocytes are involved in the pathogenesis of …

Neutrophils constitute a significant proportion of recruited immune cells in many tumours.
While activated neutrophils are able to exert robust anti-tumoural effects, more often they …

Cytokine oncostatin M (OSM) plays an important role in a variety of inflammatory reactions
and is mainly produced in neutrophils in inflammatory diseases. While natural pentacyclic …

Cancer immunotherapies (CIT) stand as novel and promising strategies for the treatment of
cancer. Their aim is to enhance the individual's own immune system to recognise and …

Cervical carcinoma remains the fourth most common cause of cancer in women worldwide.
Cytological screening and introduction of prophylactic HPV vaccines have drastically …

Tese (Doutorado em Biociências)–Instituto de Biologia Roberto Alcântara Gomes,
Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2021. Macrófagos são células …

Abstract mTORC1 is one of the central modulators of inflammation and tumorigenesis in the
gastrointestinal tract. This is supported by the benefits afforded by pharmaceutical inhibitors …

Methods and results We queried Genotype-Tissue Expression data and found rs13168867
(C allele) and rs10491509 (A allele) to be associated with decreased OSMR and increased …

Objective To investigate the prognostic value of systemic immune inflammatory index (SⅡ),
neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and lymphocyte to …