Nanoparticles promise to improve the treatment of cancer through their increasingly
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …

Tumor immunology is undergoing a renaissance due to the recent profound clinical
successes of tumor immunotherapy. These advances have coincided with an exponential …

Biological macromolecules encode information: some of it to endow the molecule with
structural flexibility, some of it to enable molecular actions as a catalyst or a substrate, but a …

These days many leading scientists argue for a new paradigm for cancer research and
propose a complex systems-view of cancer supported by empirical evidence. As an …

Biological paths of tumor progression are difficult to predict without time-series data. Using
median shift and abacus transformation in the analysis of RNA sequencing data sets, natural …

Novel therapies are needed to treat Parkinson's disease (PD) in which the clinical unmet
need is pressing. Currently, no clinically available therapeutic strategy can either retard or …

VENTURER was one of the first three UK government funded research and innovation
projects on Connected Autonomous Vehicles (CAVs) and was conducted predominantly in …

This chapter describes the general principles and basics of personalized therapy of cancer.
The biggest challenge for optimal treatment outcomes in cancer patients is the complex …

Management of cancer has been unsatisfactory in the past but an understanding of the
molecular, genetic and genomic aspects of cancer is accelerating progress in cancer …

Molecular diagnostics, the use of diagnostic testing to understand the molecular
mechanisms of an individual patient's disease, will be pivotal in the delivery of safe and …